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231 research outcomes, page 1 of 24
  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Tomas Mustelin; Kennedy Ukadike;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NIH | RESEARCH TRAINING IN RHEU... (5T32AR007108-20)

    Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. While its etiology remains elusive, current understanding suggests a multifactorial process with contributions by genetic, immunologic, hormonal, and environmental factors. A hypothesis that combi...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Neil K. Jairath; Mark Farha; Sudharsan Srinivasan; Ruple Jairath; Michael D. Green; Robert T. Dess; William C. Jackson; Adam B. Weiner; Edward M. Schaeffer; Shuang G. Zhao; ...
    Publisher: MDPI
    Project: NIH | A Precision Medicine Appr... (5P50CA186786-02)

    Meier estimates and Cox regression multivariable analyses. Results: Four immune clusters were identified, largely defined by plasma cell, CD4+ Memory Resting T Cells (CD4 MR), and M0 and M2 macrophage content (CD4 MRHighPlasma CellHighM0LowM2Mid, CD4 MRLowPlasma CellHig...

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  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Maria Rubini Gimenez; P. Elliott Miller; Carlos L. Alviar; Sean van Diepen; Christopher B. Granger; Gilles Montalescot; Stephan Windecker; Lars S. Maier; Pranas Šerpytis; Rokas Serpytis; ...
    Publisher: MDPI AG
    Project: EC | CULPRIT-SHOCK (602202), NIH | NRSA Training Core (5TL1TR001864-03), SNSF | Addressing sex inequaliti... (P400PM_180828)

    International audience; Background: Little is known about clinical outcomes of patients with acute myocardial infraction (AMI) complicated by cardiogenic shock (CS) requiring mechanical ventilation (MV). The aim of this study was to identify the characteristics, risk fa...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Celestino Sardu; Gaetano Santulli; Germano Guerra; Maria Consiglia Trotta; Matteo Santamaria; Cosimo Sacra; Nicola Testa; Valentino Ducceschi; Gianluca Gatta; Michele D' Amico; ...
    Publisher: Preprints
    Project: NIH | Targeting intracellular c... (5R00DK107895-04), NIH | INTRACELLULAR SIGNALING B... (5R01DK033823-16)

    0.05), and SERCA (HR 1.763 (1.167&ndash

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  • publication . Other literature type . Preprint . Article . 2020
    Open Access
    Authors:
    Qing Wu; Xiangxue Xiao; Yingke Xu;
    Publisher: medRxiv
    Project: NIH | Developing Model-based Bo... (1R15MD010475-01A1)

    &minus

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  • publication . Article . Other literature type . Preprint . 2020
    Open Access
    Authors:
    Soyoung Kim; Deanna J. Greene; Carolina Badke D'Andrea; Emily C. Bihun; Jonathan M. Koller; Bridget O'Reilly; Bradley L. Schlaggar; Kevin J. Black;
    Publisher: MDPI AG
    Project: NIH | PREDICTING OUTCOME IN CHI... (1K01MH104592-01), NIH | The New Tics Study: A Nov... (1R01MH104030-01A1), NIH | Washington University Ins... (4UL1TR000448-10), NIH | Core C - Model Systems Co... (1U54HD087011-01), NIH | PREDICTING OUTCOME IN CHI... (1R21NS091635-01), NIH | Washington University Ins... (3UL1RR024992-03S4)

    BackgroundPrevious studies have investigated differences in the volumes of subcortical structures (e.g., caudate nucleus, putamen, thalamus, amygdala, hippocampus) between individuals with and without Tourette syndrome (TS), as well as the relationships between these vo...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Mathews Valuparampil Varghese; Joel James; Cody A. Eccles; Maki Niihori; Olga Rafikova; Ruslan Rafikov;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NIH | Anaplerotic reprogramming... (5R01HL132918-03), NIH | HMGBG1 and Gender Differe... (5R01HL133085-02), NIH | Pulmonary Hypertension Br... (7R24HL123767-03)

    Vascular remodeling is considered a key event in the pathogenesis of pulmonary arterial hypertension (PAH). However, mechanisms of gaining the proliferative phenotype by pulmonary vascular cells are still unresolved. Due to well-established pyruvate dehydrogenase (PDH) ...

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  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Abhishek Pandey; Suresh Mereddy; Daniel Combs; Safal Shetty; Salma I. Patel; Saif Mashaq; Azizi Seixas; Kerry Littlewood; Girardin Jean-Luis; Sairam Parthasarathy;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NIH | The impact of aging on th... (5R21AG028307-02), NIH | Predictive Analytics and ... (1R56HL138377-01), NIH | The effect of insufficien... (5K01HL135452-03), NIH | Congruent Mentorship to R... (3R25NS094093-02S1), NIH | Chronic Moderate Sleep Re... (1R01HL095799-01A2), NIH | Slow wave sleep (SWS) and... (1R01AG056531-01A1), NIH | Sleep Intervention During... (5R01HL095748-04), NIH | ARIZONA PRIDE-25: TRANSLA... (2R25HL126140-05), NIH | (PQA 2) Obesity & Obs... (1R21CA184920-01), NIH | PROTEASE ACTIVATED RECEPT... (5R01HL059202-05)

    0.0001). In multivariate regression, individuals in neighborhoods with the highest income quartile were more adherent to PAP therapy than those in the lowest income quartile after adjusting for various confounders (adjusted Odds Ratio (adjOR) 1.18

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Feng Liu-Smith; Yunxia Lu;
    Persistent Identifiers
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: NIH | CORE--BIOSTATISTICS FACIL... (5P30CA062203-08)

    Background: BRCA1-Associated Protein 1 (BAP1) germline mutations predispose individuals to cancers, including uveal melanoma (UM) and cutaneous melanoma (CM). BAP1 loss is common in UM and is associated with a worse prognosis. BAP1 loss is rare in CM and the outcome is ...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Lamiaa Shalaby; Menaka Thounaojam; Amany Tawfik; Junnan Li; Khaled A. Hussein; Wan Jin Jahng; Mohamed Al-Shabrawey; Hang Fai Kwok; Manuela Bartoli; Diana Gutsaeva;
    Persistent Identifiers
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: NIH | Uric Acid and Diabetic Re... (1R01EY028714-01A1)

    ADAM17, a disintegrin and metalloproteinase 17, is a transmembrane metalloproteinase that regulates bioavailability of multiple membrane-bound proteins via ectodomain shedding. ADAM17 activity was shown to contribute to a number of vascular pathologies, but its role in ...

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231 research outcomes, page 1 of 24