• Restricted close
• CZ close
• Knowmad Institut close

The aim of this thesis was to study the possibilities for targeting in tumor immunotherapy. We studied the expression of phosphatidylserine in melanoma B16-F10 in vivo and in cell culture B16-F10 in vitro. We analyzed conditions resulting in higher expression of phosphatidylserine on tumor cells surface.

The bachelor's thesis deals with dynamic assessment and its use in different clinical groups, with the greatest emphasis on a group of younger school-aged children whose mother tongue is different from the language taught at primary school and who are at risk of dyslexia. The aim of this paper is to describe the benefits and effectiveness of using dynamic assessment with individuals from the target clinical group. The contrast between dynamic and static methods is described in the thesis. The literature overview focuses on the definition of dynamic assessment, the theories underlying it and its use in clinical groups. It further describes and defines the concept of dyslexia, the risks of dyslexia and its possible causes. The last chapter of the literature overview discusses the benefits of using dynamic assessment with children at risk of dyslexia with a different mother tongue than the language of instructions at primary school. The empirical part presents a research proposal that aims to determine which assessment approach, static or dynamic, is more accurate in predicting the risk of dyslexia in children whose mother tongue differs from the language of school instructions and also the language in which the child would be diagnosed by default.

The unexpected COVID-19 pandemic demanded a strong and firm state response in order to curb the unprecedented, multilevel crisis caused by the spread of SARS-CoV-2. The arrival of the virus in the EU in early 2020, including the terrible Italian first-wave outbreak, incited the primacy of health and life over any other right or freedom. Although understandable, this scenario raised concerns over the possibility of instrumentalization of the pandemic by the populist governments, given the affinity between the rise of populism discourse and practices in the event, or narrative, of crisis. With consideration of the conditions of the rule of law in the European Union, the quasi-autocracies of Poland and Hungary become interesting research objects. The present work describes these countries' measures and analyses their legality and compliance to the rule of law, together with considerations to the impact of said measures upon these countries' democratic institutions. Furthermore, the same operation will be performed for the Italian scenario, which leads to a comparison to be made between the three countries' pandemic managements, and, ultimately, a comparison between the Central-Eastern European populism and Western European populism. Due to the novelty of the subject, there is a lack of work on the...

Klíčová slova (anglicky): Mindset Theory, fixed mindset, growth mindset, motivation, extrinsic motivation, intrinsic motivation, performance motivation, aspirational level, self-efficiency, Abstract (in English): This diploma thesis focuses on Caroline Dweck's Mindset Theory and its application to the issue of performance motivation. The aim of the thesis was to determine the relationships between growth and fixed mindsets and performance motivation in college students. The research sample involved 158 Czech college students (60.1 % female), with average age 23 years. The data were collected using a questionnaire battery involving Performance motivation questionnaire (LMI), Dweck's mindset theory questionnaire, and Meili's aspirational test. Statistical analysis using SPSS showed that the hypothesized correlation between a specific type of mindset and performance motivation was not confirmed in our sample. However, subsequent cluster analysis showed that the students could be categorized into four groups based on their different motivational profiles. The results of the cluster analysis corresponded with theoretical propositions of the Mindset Theory. The results of the thesis can be valuable in the Czech context, in which the issue of mindset has not been sufficiently explored. In practical terms, the...

This bachelor thesis, called ?Chemical-physical paremetres of ground waters of chosen subwaters of Stropnice?, includes finding content of concentration of chemical and physical matters in water. The goal of this thesis was to compare the content of waters at ?Bedřichovský potok? and ?Pasecký potok?. Sampling and analysis of samples were made in 2010. Diagrams were made for easier presentation and to easily compare the differences. From the results we can judge, that differences are in contents of SO4, Cl, Ca and K. The biggest influence on these values has got fertilization by organic and lifestock manures.

Legal problems of biodiversity conservation, dissertation JUDr. Ji í Zicha, supervisor: prof. JUDr. Milan Damohorský, DrSc. Charles University, Faculty of Law, Department of Environemntal Law Prague, September 2010 The aim of the dissertation is to confront legal and institutional framework of conservation of biodiversity with its biological principles and most serious current threats, and assess to which extend are these systems and phenomenons in conformity and where eventually exist gaps and shortages. As a method of this confrontation was chosen an overview and analysis of relevant sources of law and other related information in the context of each level of biodiversity, and further in the context of several substantive and legal connections. With respect to characteristics of biodiversity which, similarly as other components of environment, does not respect borders created artificially by man, international law of global and regional scope plays a crucial role. It is valid almost without any reservation for nearly homogenous marine environment, in case of terrestrial environment some physical and geographical framgmentation can be observed and the role of particular state with its internal legal regime is more important. Individual issues are therefore primarily discussed from the point of...

This bachelor's thesis aims to examine the influence of the development of information and communication technologies on media literacy. In short, it is an analysis of statistical data on the development of ICT and the subsequent implementation of this data on the empirical facts about media literacy in the Czech Republic. Main idea is focused on the gradual transition from traditional methods of transmitting media information to digitalisation and how Czech society is dealing with this change. The paper demonstrates the differences in the opportunities to access modern technologies which can display media content and examines these differences in various socio-demographic groups.

This thesis focuses on analysis of jobs in private company MAVEL a.s. Objective of this thesis is to update current jobs descriptions, which are supplemented by specification, and to create the missing description of the selected jobs. The first part of the work is theoretical base, which is elaborated by the literature and relevant web sources. The practical part discribes the company and basic characteristics of the respondents, who were all workers of studied jobs. Next part is analysis of work, which was carried out by questionnaires. The analysis result is to create jobs descriptions, whose final version is fleshed out by interview with senior staff. Updated descriptions should facilitace the selection procedure to the given positions. At the end of the work are introduced some recommendations which should lead to more effictive HR activities in the investigate company.

This diploma thesis deals with taxation of financial institutions with focus on banking sector in the Czech Republic. The aim is to analyze effective tax rate of the Czech banks, define issues that might have influenced the evolution of the effective tax rate and make comparison with effective tax rate of other Czech corporations and European banks. The first chapter characterizes financial institutions, development of taxation of the financial sector and briefly describes the global financial crises. In the next chapter specifics of the value added tax and corporate income tax are described from the point of view of the financial institutions according to the Czech law followed by description of the financial transactions tax and financial activities tax. In the third chapter is analyzed effective tax rate of the Czech banks for period from 2007 to 2014 based on data gained from annual reports of the analyzed banks. Data for comparison of the effective rates of Czech and European banks were gained from the database S&P Capital IQ. In the conclusion of the thesis are analyzed reasons that might have caused changes in the effective tax rate in the banking sector.

The aim of this bachelor thesis is to compare two, a "soft" (non-investment) and a "hard" (investment), projects which represent specific applicants' business objectives for funding grants from the EU. The thesis analyzes deriving from the structural funding of the EU in the programming period 2007 2013, it describes main pitfalls in deriving from these resources and evaluates them. The thesis also describes positive and negative aspects that come with this financial support. This bachelor thesis is divided into two parts a practical part and a theoretical part. The theoretical part describes the 2007 2013 funding programmes. The practical part is focused on the analysis of the operational programmes. It also evaluates positive and negative aspects that come with obtained funds, and the constraints associated with the project implementation.