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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Shen, Liming; Zhuang, Hongbin; Lin, Jing; Cao, Xueshan; +5 Authors

    We used a kit to extract cell membrane proteins from each type of cell. Because the maximum label of iTRAQ are eight, the biological replicates were set in HAEC and Huh7 cell and two biological replicates were set in Vero E6 cell. The t-test was used to identify DEPs. The resulting p values from both tests were adjusted to control for multiple testing using the Benjamini–Hochberg correction. Significance was set at p < 0.05. 

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ figsharearrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    Other ORP type . 2022
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    Other ORP type . 2022
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    Other ORP type . 2022
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    Other ORP type . 2022
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ figsharearrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      Other ORP type . 2022
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    Non food pubs in Dublin continue to be only pubs not allowed to open in country. Will have been closed for minimum of 225 days.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Trinity's Access to ...arrow_drop_down
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Buda, Silke; Dürrwald, Ralf; Biere, Barbara; Reiche, Janine; +10 Authors

    Die ARE-Aktivität wird neben den für die Jahreszeit typischen Atemwegsinfektionen durch Erkältungsviren auch durch die seit der 27. KW kontinuierlich steigende Zahl von SARS-CoV-2-Infektionen und COVID-19- Erkrankungen verursacht. Der Anstieg schwerer Atemwegserkrankungen bildet sich aber bisher nicht in vergleichbarem Ausmaß ab. Ältere Menschen haben weiterhin ein höheres Risiko für einen schweren Krankheitsverlauf nach SARS-CoV-2-Infektion und sollten die Impfangebote wahrnehmen. Die Aktivität akuter respiratorischer Erkrankungen (ARE) in der Bevölkerung ist in der 41. KW 2023 im Vergleich zur 40. KW insgesamt gesunken. Im Vergleich zur Vorwoche sind die Werte in den meisten Altersgruppen gesunken, bei den Kindern im Schulalter (5 bis 14 Jahre) sind die Werte stabil geblieben. Im ambulanten Bereich ist die Zahl der Arztbesuche wegen ARE in der 41. KW im Vergleich zu den Vorwochen gestiegen. Im NRZ für Influenzaviren wurden in der 41. KW 2023 in insgesamt 78 (54 %) der 144 eingesandten Sentinelproben respiratorische Viren identifiziert, darunter hauptsächlich Rhinoviren (31 %) und SARS CoV-2 (20 %). Im Rahmen der ICD-10-Code basierten Krankenhaussurveillance (ICOSARI) ist die Zahl schwerer akuter respiratorischer Infektionen (SARI) in der 41. KW 2023 im Vergleich zur Vorwoche stabil geblieben. Unter den in der 41. KW wegen einer schweren Atemwegserkrankung hospitalisierten Patientinnen und Patienten erhielten 22 % eine COVID-19-Diagnose, 1 % der SARI-Fälle erhielt eine RSV-Diagnose. Es wurden keine Influenza-Diagnosen vergeben. Bei den Daten aus dem Meldewesen gemäß IfSG wurde für COVID-19 seit der 27. Meldewoche (MW) ein steigender Trend verzeichnet. In der Abwassersurveillance setzte sich der bisherige Trend mit steigenden Nachweiswerten in der Mehrzahl der Standorte fort. Der Anteil der SARS-CoV-2-Variante EG.5 lag in der 39. KW 2023 bei knapp 55 %. Die Variante BA.2.86 wurde seit der 34. KW bisher 16-mal in verschiedenen Bundesländern in Deutschland nachgewiesen.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Publikationsserver d...arrow_drop_down
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    PLEASE NOTE: Because the Novel Coronavirus (COVID-19) is a new virus in the human population, new information is becoming available as doctors and scientists study the virus and how it affects people. While the information contained in this pack was accurate at the time it was printed, we advise you to check the Health Protection Surveillance Centre (HPSC) website at www.hpsc.ie for the most up-to-date information. The HPSC website is updated frequently as new information about the COVID-19 becomes available. Version 5.0

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    Authors: Giglia, Dr Elena;

    Webinar held on Nov. 7 for the CIVICA consortium (Social sciences universities) - What's wrong with the current scholarly communication system (or, why do we need Open Science?) - Open Science definition and tools - Focus on research evaluation, Open Access, FAIR data, Open Science in Horizon Europe

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Juelich Shared Elect...arrow_drop_down
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    Authors: Schmedding, Andrea; Assion, Claudia; Mayer, Steffi; Brunner, Annika;

    The COVID-19 pandemic has been a great challenge, especially for families. We aimed to analyze the impact of the pandemic on childcare for and the work–family balance of pediatric surgeons in Germany. An anonymized questionnaire on the working and familial situation before and during the COVID-19 pandemic was sent to the members of the German Society of Pediatric Surgery and trainees in pediatric surgery (April–July 2021). One-hundred-fifty-three participants (59% female) completed the questionnaire. A total of 16% of the males and 62% of the females worked part-time. Most (68%) had underage children. During the COVID-19 pandemic, 36% reported a decrease in patients and interventions, and 55% reported an increase in the organizational workrelated burden. Childcare for underage children during lockdown was organized mainly with the help of institutional emergency childcare (45%), staying home (34%), one parent working from a home office (33%), or staying home by themselves (34%). Before the lockdown, 54% reported a good work–family balance. During the lockdown, this worsened by 42%. Most of the families had to organize themselves. Different means such as a home office, flexible working hours, and different models for childcare can help to improve the situation.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Qucosa - Publikation...arrow_drop_down
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    Authors: Robert Koch-Institut; Buda, Silke; Dürrwald, Ralf; Biere, Barbara; +10 Authors

    Die Aktivität der akuten Atemwegserkrankungen (ARE-Raten) in der Bevölkerung (GrippeWeb) ist in der 12. KW 2022 im Vergleich zur Vorwoche leicht gestiegen. Im ambulanten Bereich (Arbeitsgemeinschaft Influenza) wurden in der 12. KW bundesweit weniger Arztbesuche wegen ARE registriert als in der Vor-woche. Die Werte der ARE-Konsultationsinzidenz liegen in der 12. KW im Bereich der jährlichen Grippewellen vor der COVID-19-Pandemie. Im NRZ für Influenzaviren wurden in der 12. KW 2022 in insgesamt 77 (66 %) der 117 eingesandten Sentinelproben respiratorische Viren identifiziert, darunter 34 (29 %) Proben mit SARS-CoV-2, jeweils 16 (14 %) mit humanen Metapneumoviren (hMPV) bzw. humanen saisonalen Coronaviren (hCoV), 10 (9 %) mit Rhinoviren, acht (7 %) mit Influenzaviren, sechs (5 %) mit Parainfluenzaviren (PIV) und zwei (2 %) mit Respiratorischen Synzytialviren (RSV). Im Rahmen der ICD-10-Code basierten Krankenhaussurveillance (ICOSARI) ist die Zahl schwerer akuter respiratorischer Infektionen (SARI) seit der 2. KW 2022 insgesamt weitestgehend stabil. Für die 12. Meldewoche (MW) 2022 wurden nach Infektionsschutzgesetz (IfSG) bislang 574 labordia-gnostisch bestätigte Influenzafälle an das Robert Koch-Institut übermittelt (Stand: 29.3.2022). Die Influenza-Aktivität in Deutschland ist im Vergleich zur Vorwoche nicht weiter angestiegen. Eine Grippewelle (nach Definition der AGI) auf Bevölkerungsebene hat bisher nicht begonnen. Die ARE-Aktivität in Deutschland wird in der Bevölkerung und im ambulanten Bereich weiterhin durch die Omikron-Welle mitbestimmt, im stationären Bereich ist COVID-19 weiterhin die häufigste Erkrankung unter allen schweren Atemwegsinfektionen.

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Shen, Liming; Zhuang, Hongbin; Lin, Jing; Cao, Xueshan; +5 Authors

    We used a kit to extract cell membrane proteins from each type of cell. Because the maximum label of iTRAQ are eight, the biological replicates were set in HAEC and Huh7 cell and two biological replicates were set in Vero E6 cell. The t-test was used to identify DEPs. The resulting p values from both tests were adjusted to control for multiple testing using the Benjamini–Hochberg correction. Significance was set at p < 0.05. 

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    Non food pubs in Dublin continue to be only pubs not allowed to open in country. Will have been closed for minimum of 225 days.

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    Authors: Buda, Silke; Dürrwald, Ralf; Biere, Barbara; Reiche, Janine; +10 Authors

    Die ARE-Aktivität wird neben den für die Jahreszeit typischen Atemwegsinfektionen durch Erkältungsviren auch durch die seit der 27. KW kontinuierlich steigende Zahl von SARS-CoV-2-Infektionen und COVID-19- Erkrankungen verursacht. Der Anstieg schwerer Atemwegserkrankungen bildet sich aber bisher nicht in vergleichbarem Ausmaß ab. Ältere Menschen haben weiterhin ein höheres Risiko für einen schweren Krankheitsverlauf nach SARS-CoV-2-Infektion und sollten die Impfangebote wahrnehmen. Die Aktivität akuter respiratorischer Erkrankungen (ARE) in der Bevölkerung ist in der 41. KW 2023 im Vergleich zur 40. KW insgesamt gesunken. Im Vergleich zur Vorwoche sind die Werte in den meisten Altersgruppen gesunken, bei den Kindern im Schulalter (5 bis 14 Jahre) sind die Werte stabil geblieben. Im ambulanten Bereich ist die Zahl der Arztbesuche wegen ARE in der 41. KW im Vergleich zu den Vorwochen gestiegen. Im NRZ für Influenzaviren wurden in der 41. KW 2023 in insgesamt 78 (54 %) der 144 eingesandten Sentinelproben respiratorische Viren identifiziert, darunter hauptsächlich Rhinoviren (31 %) und SARS CoV-2 (20 %). Im Rahmen der ICD-10-Code basierten Krankenhaussurveillance (ICOSARI) ist die Zahl schwerer akuter respiratorischer Infektionen (SARI) in der 41. KW 2023 im Vergleich zur Vorwoche stabil geblieben. Unter den in der 41. KW wegen einer schweren Atemwegserkrankung hospitalisierten Patientinnen und Patienten erhielten 22 % eine COVID-19-Diagnose, 1 % der SARI-Fälle erhielt eine RSV-Diagnose. Es wurden keine Influenza-Diagnosen vergeben. Bei den Daten aus dem Meldewesen gemäß IfSG wurde für COVID-19 seit der 27. Meldewoche (MW) ein steigender Trend verzeichnet. In der Abwassersurveillance setzte sich der bisherige Trend mit steigenden Nachweiswerten in der Mehrzahl der Standorte fort. Der Anteil der SARS-CoV-2-Variante EG.5 lag in der 39. KW 2023 bei knapp 55 %. Die Variante BA.2.86 wurde seit der 34. KW bisher 16-mal in verschiedenen Bundesländern in Deutschland nachgewiesen.

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    PLEASE NOTE: Because the Novel Coronavirus (COVID-19) is a new virus in the human population, new information is becoming available as doctors and scientists study the virus and how it affects people. While the information contained in this pack was accurate at the time it was printed, we advise you to check the Health Protection Surveillance Centre (HPSC) website at www.hpsc.ie for the most up-to-date information. The HPSC website is updated frequently as new information about the COVID-19 becomes available. Version 5.0

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    Authors: Giglia, Dr Elena;

    Webinar held on Nov. 7 for the CIVICA consortium (Social sciences universities) - What's wrong with the current scholarly communication system (or, why do we need Open Science?) - Open Science definition and tools - Focus on research evaluation, Open Access, FAIR data, Open Science in Horizon Europe

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    Authors: Schmedding, Andrea; Assion, Claudia; Mayer, Steffi; Brunner, Annika;

    The COVID-19 pandemic has been a great challenge, especially for families. We aimed to analyze the impact of the pandemic on childcare for and the work–family balance of pediatric surgeons in Germany. An anonymized questionnaire on the working and familial situation before and during the COVID-19 pandemic was sent to the members of the German Society of Pediatric Surgery and trainees in pediatric surgery (April–July 2021). One-hundred-fifty-three participants (59% female) completed the questionnaire. A total of 16% of the males and 62% of the females worked part-time. Most (68%) had underage children. During the COVID-19 pandemic, 36% reported a decrease in patients and interventions, and 55% reported an increase in the organizational workrelated burden. Childcare for underage children during lockdown was organized mainly with the help of institutional emergency childcare (45%), staying home (34%), one parent working from a home office (33%), or staying home by themselves (34%). Before the lockdown, 54% reported a good work–family balance. During the lockdown, this worsened by 42%. Most of the families had to organize themselves. Different means such as a home office, flexible working hours, and different models for childcare can help to improve the situation.

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