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An auditory ERP (Event-Related Potentials) paradigm based on auditory stream segregation for 3-class BCI application was investigated by EEG measurements. This dataset contains 64ch EEG (electroencephalography) and 2ch EOG (electrooculography) recorded data.

Abstract Background Stroke management require rapid identification, assessment, and transport of patients to qualified health care centers. However, there is little description in the literature on the multiple challenges associated with the pre-hospital transport of suspected stroke patients. Objective To characterize the pre-hospital care provided to suspected stroke patients by the Brazilian Emergency Medical Service (SAMU in Portuguese), by means of a descriptive case study. Methods This is a descriptive study of a series of cases. Data from the SAMU regarding the responses to emergency calls from suspected stroke patients were collected. Independent reviewers confirmed the diagnostic hypothesis and all discordances were assessed using kappa statistics. Clinical data and transport times were described as frequency and proportion or central tendency and dispersion measures. Normality of continuous variable distribution was assessed using the Kolmogorov-Smirnov test. The Mann-Whitney U test was used for comparison of medians, with a 5% significance level. Results During the studied period, 556 suspected stroke patients were treated. The kappa index was 0.82 (95% CI 0.737 to 0.919) CI. In 74.7% of the cases, the symptom onset time was not recorded. The median time elapsed between the call for emergency services and the ambulance arrival was 18 minutes, and the median transport time was 38 minutes. A total of 34% of the patients were taken to referral hospitals for stroke. Conclusion This study revealed a low level of knowledge regarding the need to determine the exact time of symptom onset of suspected stroke patients. Also, the study showed the low rate of patients taken to referral hospitals. (Int J Cardiovasc Sci. 2021; [online].ahead print, PP.0-0)

Additional file 1:. Supplementary data.

Additional file 1. Analysis of the movement and force strategies applied to solve the task. We analyzed the strategies used by the subjects for accomplishing the tasks, to verify if they can provide further explanations of the results presented in the manuscript. In Experiment 1 we found that the loading conditions influenced the kinematic strategy during the position matching task. In Experiment 2 the strategy adopted for bimanual force exertion was not influenced by symmetric/asymmetric arm configurations, but by handedness or hand preference effects. Figure S1. Example of speed and force profile.

Figure S4. Hippocampus RNA-seq significantly enriched KEGG pathway annotations. KEGG pathways significantly enriched in genes that were differentially expressed in hippocampus of CORT + DFP exposed mice. (CSV 3Â kb)

Gene size and fold change expression breakdown for CNS cell type-specific DE genes. Significant DE genes with CNS cell type-specific designations were broken down into 4 categories—(1) decreased expression, gene size 100 kb (light orange); (3) increased expression, gene size 100 kb (red). Within each category, DE genes are organized by their respective CNS cell type-specific distribution. The exact Log2 fold change and gene size (kb) values are listed for each DE gene. File format: Microsoft Excel spreadsheet. (XLS 66 kb)

This dataset contains cytoarchitectonic maps of Area ifj1 (IFS/PreCS) in the BigBrain. The mappings were created using cytoarchitectonic criteria applied on digitized histological sections of 1 ��m resolution, cut in coronal plane. Areal borders have been detected by an oberserver-independent border definition (Schleicher 2000). Mappings are available on sections of the BigBrain and have been transformed to the 3D reconstructed BigBrain space using the transformations used in Amunts et al. 2013. From these delineations, a preliminary 3D map of Area ifj1 (IFS/PreCS) has been created by simple interpolation of the coronal contours in the 3D anatomical space of the Big Brain. This map gives a first impression of the location of this area in the Big Brain, and can be viewed in the atlas viewer using the URL below.

This archive contains sample output files for the sample data accompanying the Princeton Handbook for Reproducible Neuroimaging. Outputs include the NIfTI images converted using HeuDiConv (v0.8.0) and organized according to the BIDS standard, quality control evaluation using MRIQC (v0.15.1), data preprocessed using fMRIPrep (v20.2.0), and other auxiliary files. All outputs were created according to the procedures outlined in the handbook, and are intended to serve as a didactic reference for use with the handbook. The sample data from which the outputs are derived were acquired (with informed consent) using the ReproIn naming convention on a Siemens Skyra 3T MRI scanner. The sample data include a T1-weighted anatomical image, four functional runs with the “prettymouth” spoken story stimulus, and one functional run with a block design emotional faces task, as well as auxiliary scans (e.g., scout, soundcheck). The “prettymouth” story stimulus created by Yeshurun et al., 2017 and is available as part of the Narratives collection, and the emotional faces task is similar to Chai et al., 2015. The brain data are contributed by author S.A.N. and are authorized for non-anonymized distribution.

Purpose: To investigate the feasibility of a study based on treatment with topiramate (TPM) added to moderate hypothermia in newborns with hypoxic ischemic encephalopathy (HIE). Materials and methods: Multicenter randomized controlled trial. Term newborns with precocious metabolic, clinical and electroencephalographic (EEG) signs of HIE were selected according to their amplified integrated EEG pattern and randomized to receive either TPM (10 mg/kg once a day for the first three days of life) plus moderate hypothermia or hypothermia alone. Safety was assessed by monitoring cardiorespiratory parameters and blood samples collected to check renal, liver, metabolic balance and TPM pharmacokinetics. Efficacy was evaluated by the combined frequency of mortality and severe neurological disability as primary outcome. Incidence of magnetic resonance injury, epilepsy, blindness, hearing loss, neurodevelopment at 18–24 months of life was assessed as secondary outcomes. Results: Forty-four asphyxiated newborns were enrolled in the study. Twenty one newborns (10 with moderate and 11 with severe HIE) were allocated to hypothermia plus TPM and 23 (12 moderate and 11 severe HIE) to hypothermia. No statistically or clinically significant differences were observed for safety, primary or secondary outcomes. However, a reduction in the prevalence of epilepsy was observed in newborns co-treated with TPM. Conclusions: Results of this pilot trial suggest that administration of TPM in newborns with HIE is safe but does not reduce the combined frequency of mortality and severe neurological disability. The role of TPM co-treatment in preventing subsequent epilepsy deserves further studies.