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Database COVID

EXCLI Journal; 20:Doc276; ISSN 1611-2156

In Brazil, the last country in the Americas to abolish slavery, the effects of colonization reverberate in the insurgence of a necropolitics that directly affects Black youth and children. According to the Brazilian Forum of Public Safety, between the years of 2016 and 2020, 35 thousand people from 0 to 17 years old were killed in violent ways. In 2021, around 7 children or teenagers were victims of lethal violence per day. For such, the text updated the condition of contemporary necropolitics considering its colonizing genealogy, having as central axis the comprehension of «the complex of Miguel Otávio», (Souza and Carvalho, 2022, p. 7) as the capacity whether rational or not, conscious or unconscious, of adultcentrism to banalize the risks to which children are submitted, to the point of dying in gratuitous, stupid, violent, irresponsible and negligent forms. Considering examples such as Miguel Otávio Santana, who was 4 years old and was killed due to infant abandonment, and João Pedro Mattos, who was 14 years old and was shot by the police with a rifle, both cases taking place in the most rigid period of the COVID-19 quarantine, it is possible to understand that such processes educate the Brazilian society to treat differences as a synonym to inequalities and that adultcentrism is key in the composition of the Brazilian racism that sustains the death of Black children. Educazione interculturale, Vol. 21 No. 1 (2023): Education in a world of conflict and division

Com o objetivo de frear o número de infecções por COVID-19, vários países adotaram regulamentações de distanciamento social, incluindo o fechamento de estabelecimentos não essenciais e restrições de mobilidade. Este artigo estima o impacto dessas regulamentações sobre os crimes contra a propriedade no estado de São Paulo. O impacto é estimado usando um modelo espaço-temporal Bayesiano e é desagregado por microrregiões. A variabilidade espacial do impacto é usada para inferir quais variáveis observadas caracterizam os locais com maior probabilidade de terem sido impactados. Os resultados indicam que a maioria das microrregiões sofreu uma redução nos crimes contra a propriedade e que esses locais são caracterizados por índices de isolamento mais altos e menos recebimento de transferências emergenciais de dinheiro. With the goal of stopping COVID-19 infections, several countries adopted social distancing regulations, including closure of non essential establishments and mobility restrictions. This paper estimates the impact of these regulations on property crime in the state of São Paulo. The impact is estimated using a Bayesian spatiotemporal model, and is disaggregated by microregions. The space variability of the impact is used to infer which observed variables characterize places with higher probability of impact. We found that most microregions experienced a decrease in property crime, and that these places are characterized by higher isolation indices and less receipt of emergency cash transfers.

Abstract COVID-19 pandemic has required social isolation to prevent the virus from spreading. Initially, the elderly were the most affected by the novel coronavirus. However, the virus spread out worldwide, affecting all age groups. The elderly are commonly affected by several chronic diseases, and as a consequence of social isolation caused by the COVID-19 pandemic, the community-based exercise programs, which usually provide health and well-being to the elderly, have stopped their activities to avoid the virus to spread out; so, the elderly kept taking medicines but stopped exercising, which must impair their health and increase demand from the public health system. In this sense, the physical education professional is essential to providing safe approaches to the elderly who are not able to enroll in community-based exercise programs but need to exercise to improve their health. This article aims to discuss the consequences of not exercising in older adults’ health during the social isolation caused by the COVID-19 pandemic; still, we intend to present adjunct strategies to allow the elderly to exercise even socially isolated.

SARS-CoV-2 (SCoV2) and its variants of concern pose serious challenges to the public health. The variants increased challenges to vaccines, thus necessitating for development of new intervention strategies including anti-virals. Within the international Covid19-NMR consortium, we have identified binders targeting the RNA genome of SCoV2. We established protocols for the production and NMR characterization of more than 80 % of all SCoV2 proteins. Here, we performed an NMR screening using a fragment library for binding to 25 SCoV2 proteins and identified hits also against previously unexplored SCoV2 proteins. Computational mapping was used to predict binding sites and identify functional moieties (chemotypes) of the ligands occupying these pockets. Striking consensus was observed between NMR-detected binding sites of the main protease and the computational procedure. Our investigation provides novel structural and chemical space for structure-based drug design against the SCoV2 proteome. Angewandte Chemie. International Edition, 61 (46) ISSN:0570-0833 ISSN:1433-7851 ISSN:1521-3773

Estamos atravessando uma crise humanitária multidimensional sobre a qual temos mais questionamentos que certezas, e neste cenário, as questões relacionadas à saúde mental geram grande preocupação. Assim, o presente estudo teve como objetivo compreender de que forma o pensamento crítico tem abordado as questões relacionadas à saúde mental em tempos de pandemia de Covid-19. A metodologia utilizada foi a pesquisa bibliográfica, através do estudo de publicações científicas em periódicos e livros, configurando-se uma investigação analítica e crítico-argumentativa. Como resultado, compreendeu-se que para os diferentes autores do pensamento crítico, em especial no contexto latino-americano, é necessário a construção de um outro mundo para além da exploração, um exemplo é a utopia do bem viver, que, desde o mundo andino, ameríndio, feminista tem coproduzido ações coletivas que apontam para novas formas de viver.

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Pandemics are here since the dawn of mankind. History records the most diverse diseases, epidemics and pandemics which in certain historical particularities and situations have afflicted tribes, communities, towns, cities and entire nations. Pandemics are a striking remind of the irrepressible bond between the human being and nature, which is naturally human and humanly natural. The diseases, with great capacity for dissemination and contagion, have devastated even the most fortified cities, as was the case with the Anthonina plague that struck Rome in 165. The pandemic that occurred in the Roman Empire began with the troops that were installed in the Parthia, a Roman territory located in Mesopotamia. Through these troops, the disease arrived in Rome in 166 and was the cause of up to two thousand deaths a day {Citation}. Studies indicate it was probably an outbreak of smallpox. It is estimated that 5 million people died as a result of the Anthonina plague.