Quick search
Advanced search in
Field to searchTerm
Add rule
Filters (2)
Download Results
32,332 research outcomes, page 1 of 3,234
  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Jessica Julia Falk; Martina Winkelmann; Kerstin Laib Sampaio; Caroline Paal; Hubert Schrezenmeier; Mira Alt; Richard J. Stanton; Adalbert Krawczyk; Ramin Lotfi; Christian Sinzger;
    Persistent Identifiers
    Publisher: MDPI AG

    Immunoglobulins are only moderately effective for the treatment of human cytomegalovirus\ud (HCMV) infections, possibly due to ineffectiveness against cell-associated virus spread. To overcome\ud this limitation, we aimed to identify individuals with exceptional antibod...

    Add to ORCIDorcid
  • publication . Conference object . 2015
    Open Access English
    Authors:
    Zhang, L.; Chiaradia, Alain J.; Zhuang, Y;
    Publisher: Springer International Publishing

    Between 1993 and 2013, the high-capacity metro network of Shanghai has expanded rapidly and played a major part in the sustainable public transportation system. In this short period, the major change in accessibility introduced by the metro system kept pace with massive...

  • publication . Article . 2010
    Open Access English
    Authors:
    Andy Fenton; Sarah E. Perkins;
    Persistent Identifiers
    Publisher: Cambridge University Press

    SUMMARYPredator-prey models are often applied to the interactions between host immunity and parasite growth. A key component of these models is the immune system's functional response, the relationship between immune activity and parasite load. Typically, models assume ...

    Add to ORCIDorcid
  • publication . Article . 2019
    Open Access English
    Authors:
    Frances J. Langdon; Caroline Daly; Emmajane Milton; Ken Jones; Melanie J. Palmer;
    Persistent Identifiers
    Publisher: UCL IOE Press

    Findings from the Langdon Induction and Mentoring Survey conducted in schools employing newly qualified teachers (NQTs) in New Zealand and Wales suggest that schools should not be left to determine how they 'do' induction within national policy frameworks. The survey ex...

    Add to ORCIDorcid
  • publication . Part of book or chapter of book . 2019
    Open Access English
    Authors:
    Smith, Daniel;
    Publisher: SAGE
  • publication . Article . 2013
    Open Access
    Authors:
    Rees, E; Kirov, G; Sanders, A; Walters, J T R; Chambert, K D; Shi, J; Szatkiewicz, J; O'Dushlaine, C; Richards, A L; Green, E K; ...
    Persistent Identifiers
    Publisher: Springer Nature
    Project: NIH | The Collaborative Genetic... (5P01CA089392-03), NIH | Statistical Methods for G... (5R01CA133996-02), EC | EU-GEI (241909), NIH | CA: Administrative Core (5P50CA097007-07), NIH | Pilot: Treatment effects ... (3P50CA084724-04S1), NIH | Genome Wide Association C... (5U01HG004446-04), UKRI | Molecular Genetics of Sch... (G0800509), NIH | Molecular Epidemiology of... (5R01ES011740-09), NIH | 2/2-A Large-Scale Schizop... (1R01MH095034-01A1), WT | Understanding the genetic... (090532),...

    A number of large, rare copy number variants (CNVs) are deleterious for neurodevelopmental disorders, but large, rare, protective CNVs have not been reported for such phenotypes. Here we show in a CNV analysis of 47 005 individuals, the largest CNV analysis of schizophr...

    Add to ORCIDorcid
  • publication . Article . 2015
    Open Access English
    Authors:
    Martin John Scurr; Clare M. Brown; Diana Filipa Costa Bento; Gareth James Betts; B. I. Rees; Robert Kerrin Hills; Awen Gallimore; Andrew James Godkin;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: WT | Identification of mechani... (086983), UKRI | Characterisation of Posit... (G0801190)

    Current dogma suggests that tumor-reactive IFN-γ–producing (TH1-type) T-cells are beneficial to patient outcome; however, the clinical consequence of these responses with respect to long-term prognosis in colorectal cancer (CRC) is not understood. Here, we compared the ...

    Add to ORCIDorcid
  • publication . Article . 2018
    Open Access English
    Authors:
    Jakubowska, Monika A; Kerkhofs, Martijn; Martines, Claudio; Efremov, Dimitar G; Gerasimenko, Julia V; Gerasimenko, Oleg V; Petersen, Ole H; Bultynck, Geert; Vervliet, Tim; Ferdek, Pawel E;
    Persistent Identifiers
    Publisher: Wiley
    Project: UKRI | MICA: Calcium signalling,... (MR/J002771/1)

    BACKGROUND AND PURPOSE: Many cancer cells depend on anti-apoptotic B-cell lymphoma 2 (Bcl-2) proteins for their survival. Bcl-2 antagonism through Bcl-2 homology 3 (BH3) mimetics has emerged as a novel anti-cancer therapy. ABT-199 (Venetoclax), a recently developed BH3 ...

    Add to ORCIDorcid
  • publication . Article . 2019
    Open Access English
    Authors:
    Ze Tao; Tiago Marcos Alves;
    Persistent Identifiers
    Publisher: Elsevier

    Throw-distance (T-D) and throw-depth (T-Z) plots are widely used by researchers and industry to examine the growth of normal faults. This study uses high-quality three-dimensional (3D) seismic and outcrop information to review the effect of data sampling on the interpre...

    Add to ORCIDorcid
  • publication . Article . Other literature type . 2010
    Open Access English
    Authors:
    Richard J. Stanton; Katarina Baluchova; Derrick J. Dargan; Charles Cunningham; Orla Sheehy; Sepehr Seirafian; Brian P. McSharry; M. Lynne Neale; James A. Davies; Peter Tomasec; ...
    Publisher: American Society for Clinical Investigation

    Human cytomegalovirus (HCMV) in clinical material cannot replicate efficiently in vitro until it has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the passaged strains used for research. To generate a genetically intact source of HCMV, we c...

    Add to ORCIDorcid
32,332 research outcomes, page 1 of 3,234