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We present an explicit analysis of wave-resonant instability of swirling flows inside fast rotating cylindrical containers. The linear dynamics are decomposed into the interaction between the horizontal inner centrifugal edge waves, the outer vertical gravity waves with the aim of understanding the dynamics of the centrifugal waves. We show how the far field velocity induced respectively by the centrifugal and the gravity waves affect each other's propagation rates and amplitude growth. We follow this with an analysis of the instability in terms of a four wave interaction, two centrifugal and two gravity ones, and explain why the resonant instability can be obtained only between a pair of two counter-propagating waves, one centrifugal and one gravity. Furthermore, a near resonant regime which does not yield instability is shown to result from a phase-locking configuration between a pair of a counter-propagating centrifugal wave and a pro-propagating gravity one, where the interaction affects the waves' propagation rates but not the amplitude growth.

Mode-dependent loss (MDL) is known to be a major issue in space-division multiplexed (SMD) systems. Its effect on performance is complex as it affects both the data carrying signal and the accumulated amplification noise. In this paper we propose a procedure for characterizing the MDL of SDM systems by means of standard measurements that are routinely performed on SDM setups. The figure of merit that we present for quantifying MDL incorporates the effect on the transmitted signal and the noise and is directly related to the spectral efficiency reduction.

Active galactic nuclei (AGN) are prominent environments for stellar capture, growth and formation. These environments may catalyze stellar mergers and explosive transients, such as thermonuclear and core-collapse supernovae (SNe). SN explosions in AGN discs generate strong shocks, leading to unique observable signatures. We develop an analytical model which follows the evolution of the shock propagating in the disc until it eventually breaks out. We derive the peak luminosity, bolometric lightcurve, and breakout time. The peak luminosities may exceed $10^{45}$ erg s$^{-1}$ and last from hours to days. The brightest explosions occur in regions of reduced density; either off-plane, or in discs around low-mass central black holes ($\sim 10^6\ M_\odot$), or in starved subluminous AGNs. Explosions in the latter two sites are easier to observe due to a reduced AGN background luminosity. We perform suites of 1D Lagrangian radiative hydrodynamics SNEC code simulations to validate our results and obtain the luminosity in different bands, and 2D axisymmetric Eulerian hydrodynamics code HORMONE simulations to study the morphology of the ejecta and its deviation from spherical symmetry. The observed signature is expected to be a bright blue, UV, or X-ray flare on top of the AGN luminosity from the initial shock breakout, while the subsequent red part of the lightcurve will largely be unobservable. We estimate the upper limit for the total event rate to be $\mathcal{R}\lesssim 100\ \rm yr^{-1}\ Gpc^{-3}$ for optimal conditions and discuss the large uncertainties in this estimate. Future high-cadence transient searches may reveal these events. Some existing tidal disruption event candidates may originate from AGN supernovae. Accepted to MNRAS

We consider a compartmental model for ribosome flow during RNA translation called the RFM. This model includes a set of positive transition rates that control the flow from every site to the consecutive site. It has been shown that when these rates are time-varying and jointly T-periodic every solution of the RFM converges to a unique periodic solution with period T. In other words, the RFM entrains to the periodic excitation. In particular, the protein production rate converges to a unique T-periodic pattern. From a biological point of view, one may argue that the average of the periodic production rate, and not the instantaneous rate, is the relevant quantity. Here, we study a problem that can be roughly stated as: can periodic rates yield a higher average production rate than constant rates? We rigorously formulate this question and show via simulations, and rigorous analysis in one simple case, that the answer is no.

AbstractThe number and distribution of recessive alleles in the population for various diseases are not known at genome-wide-scale. Based on 6447 exome-sequences of healthy, genetically-unrelated Europeans of two distinct ancestries, we estimate that every individual is a carrier of at least 2 pathogenic variants in currently known autosomal recessive (AR) genes, and that 0.8-1% of European couples are at-risk of having a child affected with a severe AR genetic disorder. This risk is 16.5-fold higher for first cousins, but is significantly more increased for skeletal disorders and intellectual disabilities due to their distinct genetic architecture.

We introduce a discrete model for binary spin-orbit-coupled (SOC) Bose-Einstein condensates (BEC) trapped in a deep one-dimensional optical lattice. Two different types of the couplings are considered, with spatial derivatives acting inside each species, or between the species. The discrete system with inter-site couplings dominated by the SOC, while the usual hopping is negligible, \textit{emulates} condensates composed of extremely heavy atoms, as well as those with opposite signs of the effective atomic masses in the two components.\ Stable localized composite states of miscible and immiscible types are constructed. The effect of the SOC on the immiscibility-miscibility transition in the localized complexes, which emulates the phase transition between insulating and conducting states in semiconductors, is studied. Comment: Journal of Physics B , in press

We discuss the spectrum phenomenon for Lipschitz functions on the infinite-dimensional torus. Suppose that [Formula: see text] is a measurable, real-valued, Lipschitz function on the torus [Formula: see text]. We prove that there exists a number [Formula: see text] with the following property: For any [Formula: see text], there exists a parallel, infinite-dimensional subtorus [Formula: see text] such that the restriction of the function [Formula: see text] to the subtorus [Formula: see text] has an [Formula: see text]-norm of at most [Formula: see text].

Abstract We present an open-source MATLAB package, entitled OpenPIV-MATLAB, for analyzing particle image velocimetry (PIV) data. We extend the PIV analysis with additional tools for post-processing the PIV results including the estimation of aero/hydrodynamic forces from the PIV data of a wake behind an immersed (bluff or streamlined) body. The paper presents a detailed description of the packages, covering the three main parts: generating two-dimensional two component velocity fields from pairs of images (OpenPIV-MATLAB), spatial and temporal flow analysis based on the velocity fields (Spatial and Temporal Analysis Toolbox), and wake flow analysis along with the force estimates (getWAKE Toolbox). A complete analysis with a variety of post-processing capabilities is demonstrated using time-resolved PIV wake data of a freely flying European starling (Sturnus vulgaris) in a wind tunnel.

© 2016 Elyashiv et al. Natural selection at one site shapes patterns of genetic variation at linked sites. Quantifying the effects of “linked selection” on levels of genetic diversity is key to making reliable inference about demography, building a null model in scans for targets of adaptation, and learning about the dynamics of natural selection. Here, we introduce the first method that jointly infers parameters of distinct modes of linked selection, notably background selection and selective sweeps, from genome-wide diversity data, functional annotations and genetic maps. The central idea is to calculate the probability that a neutral site is polymorphic given local annotations, substitution patterns, and recombination rates. Information is then combined across sites and samples using composite likelihood in order to estimate genome-wide parameters of distinct modes of selection. In addition to parameter estimation, this approach yields a map of the expected neutral diversity levels along the genome. To illustrate the utility of our approach, we apply it to genome-wide resequencing data from 125 lines in Drosophila melanogaster and reliably predict diversity levels at the 1Mb scale. Our results corroborate estimates of a high fraction of beneficial substitutions in proteins and untranslated regions (UTR). They allow us to distinguish between the contribution of sweeps and other modes of selection around amino acid substitutions and to uncover evidence for pervasive sweeps in untranslated regions (UTRs). Our inference further suggests a substantial effect of other modes of linked selection and of adaptation in particular. More generally, we demonstrate that linked selection has had a larger effect in reducing diversity levels and increasing their variance in D. melanogaster than previously appreciated.

ABSTRACT We report the detection of a bright fast radio burst, FRB 191108, with Apertif on the Westerbork Synthesis Radio Telescope. The interferometer allows us to localize the FRB to a narrow 5 arcsec × 7 arcmin ellipse by employing both multibeam information within the Apertif phased-array feed beam pattern, and across different tied-array beams. The resulting sightline passes close to Local Group galaxy M33, with an impact parameter of only 18 kpc with respect to the core. It also traverses the much larger circumgalactic medium (CGM) of M31, the Andromeda Galaxy. We find that the shared plasma of the Local Group galaxies could contribute ∼10 per cent of its dispersion measure of 588 pc cm−3. FRB 191108 has a Faraday rotation measure (RM) of +474 $\pm \, 3$ rad m−2, which is too large to be explained by either the Milky Way or the intergalactic medium. Based on the more moderate RMs of other extragalactic sources that traverse the halo of M33, we conclude that the dense magnetized plasma resides in the host galaxy. The FRB exhibits frequency structure on two scales, one that is consistent with quenched Galactic scintillation and broader spectral structure with Δν ≈ 40 MHz. If the latter is due to scattering in the shared M33/M31 CGM, our results constrain the Local Group plasma environment. We found no accompanying persistent radio sources in the Apertif imaging survey data.