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Schedatura e metadatazione dei contenuti delle carte inerenti il corso del torrente Parma nel fondo archivistico Amministrazione Fabbriche, Acque e Strade dell'Archivio di Stato di Parma

The Covid-19 pandemic caused by the novel coronavirus SARS-CoV-2 has completely reshaped the lives of people around the world, including higher education students. Beyond serious health consequences for a proportion of those directly affected by the virus, the pandemic holds important implications for the life and work of higher education students, considerably affecting their physical and mental well-being. To capture how students perceived the first wave of the pandemic���s impact, one of the most comprehensive and large-scale online surveys across the world was conducted. Carried out between 5 May 2020 and 15 June 2020, the survey came at a time when most countries were experiencing the arduous lockdown restrictions. The online questionnaire was prepared in seven different languages (English, Italian, North Macedonian, Portuguese, Romanian, Spanish, Turkish) and covered various aspects of higher education students��� life, including socio-demographic and academic characteristics, academic life, infrastructure and skills for studying from home, social life, emotional life and life circumstances. Using the convenience sampling method, the online questionnaire was distributed to higher education students (aged 18 and over) and enrolled in a higher education institution. The final dataset consisted of 31,212 responses from 133 countries and 6 continents. The data may prove useful for researchers studying the pandemic���s impacts on various aspects of student life. Policymakers can utilize the data to determine the best solutions as they formulate policy recommendations and strategies to support students during this and any future pandemic. Acknowledgments: The extensive dataset could not be collected without the numerous international partners who provided the exceptional assistance with questionnaire translation and/or data collection. This work also acknowledges the international partners, who may have been unintentionally omitted from authorship due to the snowball recruitment technique. Special thanks go also to anonymous global survey participants for their valuable insights into the lives of students, which they shared selflessly. The authors also acknowledge the CovidSocLab project (http://www.covidsoclab.org/) as a working platform for international collaboration. Funding: The authors acknowledge the financial support from the Slovenian Research Agency (research core funding No. P5-0093).

Dimorfismo sessuale e diritto divino. Transizione sessuale e diritto matrimoniale canonico. Il transessualismo come causa di inesistenza dell'attogiuridico del matrimonio canonico. La partecipazione del transessuale alla vita della Chiesa

The toxicity and efficacy of intrathecal liposomal cytarabine (LC) were evaluated in children with central nervous system (CNS) relapsed/refractory acute leukemia/lymphoma. Thirty patients (male:female ratio 21:9; median age 9.4 years) with CNS relapsed/resistant disease were treated with intrathecal LC at dosages adjusted for age. Twenty-seven (90%) patients simultaneously received systemic chemotherapy, including concurrent high-dose cytarabine or methotrexate in 21 (70%) cases. Of 28 patients evaluable for response, 25 patients (89%) achieved CNS complete remission and three (11%) partial remission. The median number of intrathecal LC administrations per patient was 4. The cerebrospinal fluid was cleared after a median of 3 intrathecal LC administrations. Neurological toxicity ≥ grade 3 occurred in four (13%) patients. No permanent sequelae were observed. The median overall survival was 20.9 months and the 5-year probability of survival was 46%. These encouraging data suggest that intrathecal LC is well tolerated and effective in children with relapsed/refractory CNS leukemia/lymphoma.

To differentiate gonadotropin deficiency from delayed puberty in teenage boys, 0.1 mg/m2 of triptorelin, a gonadotropin-releasing hormone agonist, was administered subcutaneously at 4 AM. Serum gonadotropins and testosterone levels were determined at baseline and 4 hours after the injection. The increase in blood gonadotropin and testosterone levels was significantly greater in patients with delayed puberty than in those with gonadotropin deficiency.

Descrizione della decorazione pittorica di Villa Serego a Santa Sofia di Pindemonte di Verona