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7 research outcomes, page 1 of 1
  • publication . Article . 2018
    Open Access English
    Authors:
    Eisenberg-Bord, Michal; Mari, Muriel; Weill, Uri; Rosenfeld-Gur, Eden; Moldavski, Ofer; Castro, Inês G.; Soni, Krishnakant G.; Harpaz, Nofar; Levine, Tim P.; Futerman, Anthony H.; ...
    Country: Netherlands
    Project: UKRI | Delivering accurate struc... (BB/M011801/1), EC | MITOCHONTACTS (705853), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NIH | Phospholipids in Golgi Se... (5R01GM044530-16), NWO | A three-dimensional look ... (2300175771)

    Functional heterogeneity within the lipid droplet (LD) pool of a single cell has been observed, yet the underlying mechanisms remain enigmatic. Here, we report on identification of a specialized LD subpopulation characterized by a unique proteome and a defined geographi...

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  • publication . Article . 2018
    Open Access
    Authors:
    Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian;
    Publisher: Rockefeller University Press
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | A three-dimensional look ... (2300175771), NWO | The role of autophagy in ... (2300175628)

    Autophagy is a catabolic pathway that delivers intracellular material to the mammalian lysosomes or the yeast and plant vacuoles. The final step in this process is the fusion of autophagosomes with vacuoles, which requires SNARE proteins, the homotypic vacuole fusion an...

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  • publication . Article . 2017
    Open Access
    Authors:
    Yingying Cong; Pauline Verlhac; Fulvio Reggiori;
    Publisher: MDPI AG
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | A three-dimensional look ... (2300175771)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Landi, Alessia; Mari, Muriel; Wolf, Tobias; Kleiser, Svenja; Gretzmeier, Christine; Wilhelm, Isabel; Kiritsi, Dimitra; Thünauer, Roland; Geiger, Roger; Nyström, Alexander; ...
    Publisher: Life Science Alliance LLC
    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), EC | DRIVE (765912), EC | LEC&LIP2INVADE (282105)

    Lectins are glycan-binding proteins with no catalytic activity and ubiquitously expressed in nature. Numerous bacteria use lectins to efficiently bind to epithelia, thus facilitating tissue colonisation. Wounded skin is one of the preferred niches for Pseudomonas aerugi...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Gómez-Sánchez, Rubén; Rose, Jaqueline; Guimarães, Rodrigo; Mari, Muriel; Papinski, Daniel; Rieter, Ester; Geerts, Willie J; Hardenberg, Ralph; Kraft, Claudine; Ungermann, Christian; ...
    Country: Netherlands
    Project: SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), FWF | Architecture and function... (P 25522), EC | PRONKJEWAIL (713660), NWO | The role of autophagy in ... (2300175628), FWF | Mechanisms and hierarchy ... (P 28113), EC | AutophagosomeSealing (655027), NWO | A three-dimensional look ... (2300175771)

    The autophagy-related (Atg) proteins play a key role in the formation of autophagosomes, the hallmark of autophagy. The function of the cluster composed by Atg2, Atg18, and transmembrane Atg9 is completely unknown despite their importance in autophagy. In this study, we...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Mauthe, Mario; Langereis, Martijn; Jung, Jennifer; Zhou, Xingdong; Jones, Alex; Omta, Wienand; Tooze, Sharon A; Stork, Björn; Paludan, Søren Riis; Ahola, Tero; ...
    Country: Netherlands
    Project: WT , AKA | Mechanisms in the formati... (265997), NWO | Viral strategies to evade... (2300180032), NWO | The role of autophagy in ... (2300175628), NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), EC | XABA (282333)

    Autophagy is a catabolic process regulated by the orchestrated action of the autophagy-related (ATG) proteins. Recent work indicates that some of the ATG proteins also have autophagy-independent roles. Using an unbiased siRNA screen approach, we explored the extent of t...

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  • other research product . Other ORP type . 2017
    Open Access English
    Authors:
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

7 research outcomes, page 1 of 1