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641,136 research outcomes, page 1 of 64,114
  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Andrea D. van Dam; Mariëtte R. Boon; Jimmy F. P. Berbée; Patrick C. N. Rensen; Vanessa van Harmelen;
    Persistent Identifiers

    Obesity is a well-established risk factor for atherosclerosis. However, the mechanistic link between accumulation of adipose tissue and development of atherosclerosis is not clear. Adipose tissue comprises various depots including white adipose tissue (WAT), brown adipo...

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  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Roel Nusse; Hans Clevers;

    The WNT signal transduction cascade is a main regulator of development throughout the animal kingdom. Wnts are also key drivers of most types of tissue stem cells in adult mammals. Unsurprisingly, mutated Wnt pathway components are causative to multiple growth-related p...

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  • publication . Part of book or chapter of book . 2013
    Restricted English
    Authors:
    Horsten, PP; van der Aalst, PG; Marques, L.; Richards, G.;
  • publication . Article . Other literature type . 2013
    Open Access English
    Authors:
    Bladen, Catherine; Rafferty, Karen; Straub, Volker; Monges, Soledad; Moresco, Angélica; Dawkins, Hugh; Roy, Anna; Chamova, Teodora; Guergueltcheva, Velina; Korngut, Lawrence; ...
    Persistent Identifiers

    International audience; Duchenne muscular dystrophy (DMD) is an X-linked genetic disease, caused by the absence of the dystrophin protein. Although many novel therapies are under development for DMD, there is currently no cure and affected individuals are often confined...

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  • publication . Article . 2017
    Open Access
    Authors:
    Kasper Stentz-Olesen; E. T. Nielsen; S. de Raedt; Peter Bo Jørgensen; Ole Gade Sørensen; Bart L. Kaptein; Michael Skipper Andersen; Maiken Stilling;
    Publisher: British Editorial Society of Bone & Joint Surgery

    Objectives Static radiostereometric analysis (RSA) using implanted markers is considered the most accurate system for the evaluation of prosthesis migration. By using CT bone models instead of markers, combined with a dynamic RSA system, a non-invasive measurement of jo...

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  • publication . Article . 1988
    Restricted English
    Authors:
    Regina Kanczik; Massud Khamssi; Martin C. Michel; Otto-Erich Brodde;
    Persistent Identifiers

    Cardiac, pulmonary and renal beta-adrenoceptor density and subtype distribution were measured by radioligand binding in three rat models of acquired hypertension. Dahl salt-sensitive (DS) rats on a high-sodium diet, renal hypertensive rats and DOCA-salt rats. The result...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Lieuwe D. J. Bos; Brendon P. Scicluna; David S. Y. Ong; Olaf L. Cremer; Tom van der Poll; Marcus J. Schultz;
    Persistent Identifiers
    Publisher: American Thoracic Society

    Rationale: Two biologic phenotypes of acute respiratory distress syndrome (ARDS) have been identified based on plasma protein markers in four previous studies. Objectives: To determine if blood leukocyte gene expression is different between the "reactive" and "uninflame...

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  • publication . Article . 2011
    Closed Access English
    Authors:
    Flinterman, L.E.; Hylckama, V.A.; Cannegieter, S.C.; Rosendaal, F.R.;
    Persistent Identifiers
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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Annick V. Hartstra; Pieter F. de Groot; Diogo Mendes Bastos; Evgeni Levin; Mireille J. Serlie; Maarten R. Soeters; Ceyda Tugba Pekmez; Lars O. Dragsted; Mariëtte T. Ackermans; Albert K. Groen; ...
    Persistent Identifiers

    <p><b>Objective:</b> Insulin resistance develops prior to the onset of overt type 2 diabetes, making its early detection vital. Direct accurate evaluation is currently only possible with complex examinations like the stable isotope-based hyperinsulinemic euglycemic clam...

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  • publication . Article . 2013
    Closed Access English
    Authors:
    Liu, B.; Huizinga, T.; Toes, R.;
    Persistent Identifiers
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641,136 research outcomes, page 1 of 64,114