Quick search
Advanced search in
Field to searchTerm
Add rule
Filters (2)
Download Results
105,683 research outcomes, page 1 of 10,569
  • publication . Article . 2008
    Open Access
    Authors:
    Katrina A. Evetts; Darerca Owen; Daniel Nietlispach; Helen R. Mott; Eeson Rajendra; Keily Littlefield; Louise J. Campbell; Laura K. Bailey;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Next Section Abstract The ADP-ribosylation factor-like (Arl) family of small G proteins are involved in the regulation of diverse cellular processes. Arl2 does not appear to be membrane localized and has been implicated as a regulator of microtubule dynamics. The downst...

    Add to ORCID
  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Diana P. Raymundo; Debora Foguel; Fernando L. Palhano; Guilherme A. P. de Oliveira; Cristiane Latge; Marcius S. Almeida; Katia M. S. Cabral; Luciana Romão; Júlia Araújo de Freitas; Laizes Johanson; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    International audience; Cerebral dopamine neurotrophic factor (CDNF) is a promising therapeutic agent for Parkinson disease. As such, there has been great interest in studying its mode of action, which remains unknown. The three-dimensional crystal structure of the N te...

    Add to ORCID
  • publication . Article . 2005
    Open Access
    Authors:
    Maria Nurminskaya; Cordula Magee; Lidia Faverman; Thomas F. Linsenmayer; Philippe Galera;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Previously, we have shown that two non-canonical specificity protein (SP)-binding sites within the proximal promoter (nucleotide (nt) -139 to +5) of the chicken Col10a1 gene are involved in conferring tissue-specific expression of type X collagen to hypertrophic chondro...

    Add to ORCID
  • publication . Article . 1996
    Open Access
    Authors:
    Juan C. Slebe; Alejandro M. Reyes; Coralia I. Rivas; Juan Carlos Vera; Fernando V. Velásquez; Pablo Strobel; David W. Golde; Howard I. Scher; Rodrigo Iribarren; Juan G. Cárcamo; ...
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Genistein is a dietary-derived plant product that inhibits the activity of protein-tyrosine kinases. We show here that it is a potent inhibitor of the mammalian facilitative hexose transporter GLUT1. In human HL-60 cells, which express GLUT1, genistein inhibited the tra...

    Add to ORCID
  • publication . Article . 2004
    Open Access
    Authors:
    Reinhard Lehner; Zdravko J. Lorković; Andrea Barta; Sergiy Lopato; Monika Pexa;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Ser/Arg (SR)-rich proteins are important splicing factors in both general and alternative splicing. By binding to specific sequences on pre-mRNA and interacting with other splicing factors via their RS domain they mediate different intraspliceosomal contacts, thereby he...

    Add to ORCID
  • publication . Article . 2014
    Open Access
    Authors:
    Yong-Seok Lee; Bong-Kiun Kaang; Yong-Woo Jun; Byung-Chang Suh; Jin-A Lee; Chae Seok Lim; Deok-Jin Jang; Kun Hyung Kim; Yongsoo Park;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Phosphodiesterases (PDEs) play key roles in cAMP compartmentalization, which is required for intracellular signaling processes, through specific subcellular targeting. Previously, we showed that the long and short forms of Aplysia PDE4 (ApPDE4), which are localized to t...

    Add to ORCID
  • publication . Article . 1999
    Open Access
    Authors:
    Mukund J. Modak; Kamalendra Singh; Neerja Kaushik; Jin Jin;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Abstract To determine the catalytic role of Gln190, a member of the highly conserved LPQG motif in Moloney murine leukemia virus reverse transcriptase, we carried out site-directed mutagenesis of this residue to generate Q190N and Q190A. Both mutant proteins exhibited a...

    Add to ORCID
  • publication . Article . 2009
    Open Access
    Authors:
    Warren E. Zimmer; Da-Zhi Wang; Nickolai O. Dulin; Sebastien Taurin; Xiaochun Long; Masaaki Imamura; Nan Sethakorn; Qiang Sun; Joseph M. Miano;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Serum response factor (SRF) is a ubiquitously expressed transcription factor that binds a 10-bp element known as the CArG box, located in the proximal regulatory region of hundreds of target genes. SRF activates target genes in a cell- and context-dependent manner by as...

    Add to ORCID
  • publication . Article . 2007
    Open Access
    Authors:
    Saurabh K. Gupta; Sarah S. Durkin; Xin Guo; O. John Semmes; Michael D. Ward; Kimberly F. Fryrear;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    De novo expression of human T-cell leukemia virus type 1 Tax results in cellular genomic instability. We demonstrated previously that Tax associates with the cell cycle check point regulator Chk2 and proposed that the inappropriate activation of Chk2 provides a model fo...

    Add to ORCID
  • publication . Article . 2007
    Open Access
    Authors:
    Lars Thelander; Artur Fijolek; Anders Hofer;
    Persistent Identifiers
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)

    Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness.

    Add to ORCID
105,683 research outcomes, page 1 of 10,569