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33,800 research outcomes, page 1 of 3,380
  • publication . Article . 2021
    Open Access
    Authors:
    Zhongbo Chen; Sonja Scholz; Emil Gustavsson; John Hardy; Kerri Kinghorn;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    AbstractKnowledge of genomic features specific to the human lineage may provide insights into brain-related diseases. We leverage high-depth whole genome sequencing data to generate a combined annotation identifying regions simultaneously depleted for genetic variation ...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Merel Kindt; Marieke Soeter;
    Project: EC | ErasingFear (743263)

    The discovery in animal research that fear memories may change upon retrieval has sparked a wave of interest into whether this phenomenon of reconsolidation also occurs in humans. The critical conditions under which memory reconsolidation can be observed and targeted in...

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Asli Ayaz; Andreas Staeuble; Morio Hamada; Marie-Angela Wulf; Aman B Saleem; Fritjof Helmchen;
    Publisher: Nature Publishing Group
    Project: EC | BRAINCOMPATH (670757), SNSF | Two-photon imaging of sta... (PMPDP3_145476), SNSF | Sensorimotor integration ... (PZ00P3_161544), SNSF | Calcium imaging of cellul... (CRSII3_147660), WT | Transforming visual image... (200501)

    Nature Communications, 10 (1)

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  • publication . Article . 2019
    Open Access
    Authors:
    Marion Brickwedde; Marie C. Krüger; Hubert R. Dinse;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Cognition and perception are closely coupled to alpha power, but whether there is a link between alpha power and perceptual learning efficacy is unknown. Here we show that somatosensory alpha power can be successfully up- and down-regulated with short-term neurofeedback...

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  • publication . Article . 2019
    Open Access
    Authors:
    Christopher R. Cooney; Zoë K Varley; Lara O Nouri; Christopher J A Moody; Michael D. Jardine; Gavin H. Thomas;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: EC | TOLERATES (615709)

    Sexual selection is proposed to be a powerful driver of phenotypic evolution in animal systems. At macroevolutionary scales, sexual selection can theoretically drive both the rate and direction of phenotypic evolution, but this hypothesis remains contentious. Here, we f...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Netta Shemesh; Juman Jubran; Shiran Dror; Eyal Simonovsky; Omer Basha; Chanan Argov; Idan Hekselman; Mehtap Abu-Qarn; Ekaterina Vinogradov; Omry Mauer; ...

    The sensitivity of the protein-folding environment to chaperone disruption can be highly tissue-specific. Yet, the organization of the chaperone system across physiological human tissues has received little attention. Through computational analyses of large-scale tissue...

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  • publication . Preprint . Article . Other literature type . 2021
    Open Access English
    Authors:
    Kengo Watanabe; Kazuhiro Morishita; Xiangyu Zhou; Shigeru Shiizaki; Yasuo Uchiyama; Masato Koike; Isao Naguro; Hidenori Ichijo;
    Publisher: Cold Spring Harbor Laboratory

    Cells experience various osmotic perturbation, but cellular osmosensing mechanisms remain obscure. Here, the authors report that cells recognize osmotic stress from the inside through macromolecular crowding-driven and poly(ADP-ribose)-conditioned liquid–liquid phase se...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Marcel Mudrich; Aaron LaForge; Alessandra Ciavardini; P. O’Keeffe; Carlo Callegari; M. Coreno; Alexander Demidovich; Michele Devetta; M. Di Fraia; Marcel Drabbels; ...
    Publisher: Nature Publishing Group
    Project: NSF | PREM: Partnership between... (1828019)

    Funding from the Deutsche Forschungsgemeinschaft (MU 2347/8-1, STI 125/19-1, and the priority program 1840 QUTIF, the Carlsberg Foundation, National Science Foundation (DMR-1828019), Carl-Zeiss-Stiftung, Grant No. FIS2017-87801-P (AEI/FEDER, UE), and Swiss National Scie...

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  • publication . Article . 2017
    Open Access
    Authors:
    Shaul Yogev; Celine I. Maeder; Roshni Cooper; Mark Horowitz; Adam G. Hendricks; Kang Shen;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: NIH | SYNAPTIC FUNCTION IN THE ... (1R01NS034307-01), NIH | Patterning dendritic bran... (5R01NS082208-03)

    Microtubule dynamics are essential for axonal transport. In C. elegans, the authors show that dynein heavy chain regulates the spatial distribution of dendritic microtubules which ensures correct transport progression.

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  • publication . Article . 2020
    Open Access English
    Authors:
    Xingyu Shen; Chi P. Ting; Gong Xu; Thomas J. Maimone;
    Persistent Identifiers
    Publisher: Nature Publishing Group
    Project: SNSF | Synthesis of Complex Anti... (P2BEP2_162076), NSF | Graduate Research Fellows... (1106400), NIH | Acquisition of a Cryoprob... (1S10OD024998-01), NIH | A proposal for the purcha... (1S10RR027172-01)

    Meroterpenes are a particularly important class of biologically active bicyclo[3.3.1]nonane-containing molecules. Here, the authors report a general strategy toward these valuable targets based on abiotic annulation/rearrangement steps resulting in a concise total synth...

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33,800 research outcomes, page 1 of 3,380