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2,043 research outcomes, page 1 of 205
  • publication . Report . 2016
    Open Access
    Authors:
    Winn, Martyn; Patwardhan, Ardan; Agnel Praveen, Joseph; Lagerstedt, Ingvar;
    Persistent Identifiers
    Project: EC | BIOMEDBRIDGES (284209)

    We have developed a software pipeline, named SMaSB, to perform automated volume/shape matching. Together with a database of over 1000 volumes from the Electron Microscopy Data Bank (EMDB) and Protein Data Bank (PDB), the pipeline underpins a web service PDBeShape. These...

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  • publication . Other literature type . Preprint . 2018
    Open Access
    Authors:
    Galilee, Meytal; Alian, Akram;
    Persistent Identifiers
    Publisher: bioRxiv
    Project: EC | iNEXT (653706)

    ABSTRACTNew anti-AIDS treatments must be continually developed in order to overcome resistance mutations including those emerging in the newest therapeutic target, the viral integrase (IN). Multimerization of IN is functionally imperative and provides a forthcoming ther...

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  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Masaya Yamaguchi; Shanshan Yu; Renping Qiao; Florian Weissmann; Darcie J. Miller; Ryan T. Vanderlinden; Nicholas G. Brown; Jeremiah J. Frye; Jan-Michael Peters; Brenda A. Schulman;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: EC | PCUBE (227764)

    Abstract The anaphase-promoting complex/cyclosome (APC/C) is a massive E3 ligase that controls mitosis by catalyzing ubiquitination of key cell cycle regulatory proteins. The APC/C assembly contains two subcomplexes: the “Platform” centers around a cullin-RING-like E3 l...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Linda Cerofolini; Stefano Giuntini; Letizia Barbieri; Matteo Pennestri; Anna Codina; Marco Fragai; Lucia Banci; Enrico Luchinat; Enrico Ravera;
    Persistent Identifiers
    Project: EC | West-Life (675858), EC | iNEXT (653706), EC | INSTRUCT-ULTRA (731005)

    Abstract FlowNMR has the aim of continuously monitoring processes that occur in conditions that are not compatible with being carried out within a closed tube. However, it is sample intensive and not suitable for samples, such as proteins or living cells, that are often...

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  • publication . Article . 2017
    Open Access
    Authors:
    Janine Bowring; Maan M Neamah; Jorge Donderis; Ignacio Mir-Sanchis; Christian Alite; J. Rafael Ciges-Tomas; Elisa Maiques; Iltyar Medmedov; Alberto Marina; José R. Penadés;
    Project: EC | DUT-signal (670932), EC | BIOSTRUCT-X (283570), UKRI | Understanding a novel mec... (BB/N002873/1), WT | Understanding bacterial h... (201531), UKRI | Molecular biology of the ... (MR/M003876/1)

    Targeting conserved and essential processes is a successful strategy to combat enemies. Remarkably, the clinically important Staphylococcus aureus pathogenicity islands (SaPIs) use this tactic to spread in nature. SaPIs reside passively in the host chromosome, under the...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Grigory Sharov; Karine Voltz; Alexandre Durand; Olga Kolesnikova; Gabor Papai; Alexander G. Myasnikov; Annick Dejaegere; Adam Ben Shem; Patrick Schultz;
    Publisher: Nature Publishing Group
    Project: ANR | UNISTRA (ANR-10-IDEX-0002), ANR | INRT (ANR-10-LABX-0030), ANR | Bip:Bip (ANR-10-BINF-0003)

    The transcription co-activator complex SAGA is recruited to gene promoters by sequence-specific transcriptional activators and by chromatin modifications to promote pre-initiation complex formation. The yeast Tra1 subunit is the major target of acidic activators such as...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Guillaume Tetreau; Anne-Sophie Banneville; Elena A. Andreeva; Aaron S. Brewster; Mark S. Hunter; Raymond G. Sierra; Jean-Marie Teulon; I.D. Young; Niamh Burke; Tilman A. Grünewald; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | X-in-vivo (ANR-17-CE11-0018), NIH | DIALS: New Computational ... (5R01GM117126-02), NIH | Pacific Southwest Regiona... (1U01CK000516-01), NIH | A SYNCHROTRON RADIATION B... (5P41RR001209-14), NIH | Molecular Improvement of ... (5R01AI045817-04), NIH | A Synchroton Radiation St... (8P41GM103393-33), ANR | CBH-EUR-GS (ANR-17-EURE-0003), NIH | Highly Improved Bacterial... (1U01AI054778-01), ANR | DynOCP (ANR-18-CE11-0005)

    Cyt1Aa is the one of four crystalline protoxins produced by mosquitocidal bacterium Bacillus thuringiensis israelensis (Bti) that has been shown to delay the evolution of insect resistance in the field. Limiting our understanding of Bti efficacy and the path to improved...

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  • publication . Article . 2020
    Open Access
    Authors:
    Gabriele Stevanato; Gilles Casano; Dominik J. Kubicki; Yu Rao; Laura Esteban Hofer; Georges Menzildjian; Hakim Karoui; Didier Siri; Manuel Cordova; Maxim Yulikov; ...
    Persistent Identifiers
    Publisher: American Chemical Society (ACS)
    Project: SNSF | Extending NMR crystallogr... (200020_178860), EC | Oligo-DNP (796904)

    The development of magic-angle spinning dynamic nuclear polarization (MAS DNP) has allowed atomic-level characterization of materials for which conventional solid-state NMR is impractical due to the lack of sensitivity. The rapid progress of MAS DNP has been largely ena...

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  • publication . Project deliverable . undefined
    Open Access
    Project: EC | INSTRUCT-ULTRA (731005)

    Call 1 launched for developing new service provision of existing technologies and selection of qualifying projects

  • publication . Other literature type . 2019
    Open Access
    Authors:
    AARC Consortium; AARC Community; Appint Members;
    Publisher: Zenodo
    Project: EC | AARC2 (730941)

    This document defines a generic browser-based protocol for conveying - to services - hints about the IdPs or IdP-SP-proxies that should be used for authenticating the principal. This protocol, colloquially referred to as Identity Provider (IdP) hinting, can greatly simp...

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2,043 research outcomes, page 1 of 205