Quick search
Advanced search in
Field to searchTerm
Add rule
Download Results
60 research outcomes, page 1 of 6
  • publication . Article . Other literature type . 2015
    Open Access Russian
    Publisher: ABV-press

    Breast cancer (BC) is the most common cancer among women in Russia. One of the main treatment methods of BC is systemic chemotherapy. Multidrug resistance of tumor cells (MDR) is the important hindrance on the way to successful chemotherapy. The new data concerning mole...

    Add to ORCID
  • publication . Other literature type . Article . 2018
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Background. Multiple myeloma (MM) is a hematologic malignancy of plasma cells. The microenvironment plays a key role in MM cell survival and drug resistance through release of soluble factors, expression of adhesion molecules and release of exosomes (EXs). The role that...

    Add to ORCID
  • publication . Other literature type . Article . 2019
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    The presented review is devoted to the analysis of molecular mechanisms of action for different natural DNA-tropic compounds with established tumor preventive activity. Here we present their cancer preventive effects observed in vivo, mechanisms of DNA binding, influenc...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Spirina, L. V.; Kondakova, I. V.; Tarasenko, N. V.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>Тhe protein TRIM16 is involved in key intracellular processes, such as proliferation, cell differentiation and programmed death, including intrinsic and extrinsic apoptosis, autophagy-dependent cell death and immunogenic cell death. The TRIM16 protein acts the p...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Semyanikhina, A. V.; Rasulov, A. O.; Lyubchenko, L. N.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>Lynch syndrome was synonymous with hereditary non-polyposis colorectal cancer for a long time, however, mapping of the DNA mismatch repair (MMR) genes has led to distinguish Lynch syndrome as an independent syndromic unit from a number of Lynch-like syndromes th...

    Add to ORCID
  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    S. E. Sedykh; G. A. Nevinsky;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Bispecific antibody molecules contain two different antigen-binding centers. Particular interest in bispecific antibodies is due to their therapeutic application. Two preparations of therapeutic bispecific immunoglobulins, approved for use in the US and European countri...

    Add to ORCID
  • publication . Article . Other literature type . 2018
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>Background. It is generally accepted that crosstalk between the growth factor receptor and ER pathways implicated in tamoxifen resistance. The aim of the study was to examine the relationship between mRNA level, protein expression and gene polymorphism of the EG...

    Add to ORCID
  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Gareev, I. F.; Beylerli, O. A.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>MicroRNAs are a new class of small non-coding RNAs, a length of 18–22 nucleotides that play a decisive role as posttranscriptional regulators of gene expression. Due to the large number of genes, regulated microRNAs, microRNAs are involved in many cellular proce...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    This review is devoted to modern notions about autoantibodies (AAb) as one of classes of tumor biomarkers. Principles of humoral response by way of autoantibodies to different tumor-associated proteins in the process of malignant tumor progression are considered. During...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    The modern concept of therapy for intrahepatic cholangiocarcinoma including surgical treatment, must take into account the achievements of molecular biology and modern staging principles. A detailed understanding of the molecular genetic (genetic and epigenetic) disorde...

    Add to ORCID
60 research outcomes, page 1 of 6