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16 research outcomes, page 1 of 2
  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Nasonov, E. L.; Lila, A. M.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    <jats:p>Despite the great success in the diagnosis and treatment of immuno-inflammatory rheumatic diseases (IIRD), which led to a significant improvement in the prognosis in many patients, the fundamental medical problems of this pathology – the restoration of quality o...

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  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    E. L. Nasonov; V. I. Mazurov; Yu. V. Usacheva; E. V. Chernyaeva; Ya. Yu. Ustyugov; A. B. Ulitin; R. A. Ivanov;
    Persistent Identifiers
    Publisher: IMA Press, LLC

    The paper analyzes the key biological effects of cytokines that play a central role in the pathogenesis of immunoinflammatory rheumatic diseases. Special attention is drawn to major proinflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6)...

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  • publication . Article . Other literature type . 2017
    Open Access Russian
    Authors:
    Karateev, A. E.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    <jats:p>.</jats:p>

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Tuaeva, N. O.; Nosyrev, A. E.; Renaudineau, Y.; Arleevskaya, M. I.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    <jats:p>Molecular mechanisms of development of normal and pathological neuroendocrine and immune adaptive response to psychological (mental) stress are analyzed considering its possible provoking role in the development of rheumatoid arthritis (RA). A detailed analysis ...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Nasonov, E. L.; Korotaeva, T. V.; Lila, A. M.; Kubanov, A. A.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    <jats:p>Psoriatic arthritis (PsA) is a chronic immunoinflammatory disease that, on the one hand, is considered as the most common comorbidity in psoriasis as part of systemic psoriatic disease, and, on the other, is classified as a clinical form of spondyloarthritis and...

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  • publication . Article . Other literature type . 2018
    Open Access Russian
    Authors:
    Nasonov, E. L.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    The paper deals with the mechanisms of a T-cell immune response, which depends on the balance between costimulatory and coinhibitory signals that have been called as immune checkpoints (ICP). The imbalance of T-cell activation within ICTs (CTLA4/CD28 and PD1/PD1L) is co...

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  • publication . Article . Other literature type . 2017
    Open Access Russian
    Authors:
    Karateev, A. E.; Karateev, D. E.; Davydov, O. S.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    An inflammatory response and the development of pain are interdependent processes. Inflammation accompanied by the overproduction of proinflammatory cytokines and mediators not only causes pain, but is also the main cause of its chronicity. Therefore, the use of anti-in...

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  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    A. E. Karateev; A. M. Lila;
    Persistent Identifiers
    Publisher: IMA Press, LLC

    In recent years, there has been a trend toward changing the clinical concept of osteoarthritis (OA). This disease has been considered as an age-related disease and the long-term result of a current pathological process for a very long time. However, many experts are now...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Nasonov, E. L.; Popkova, T. V.;
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    <jats:p>Atherosclerosis is now considered as chronic inflammatory vascular disease connected to «pathological» activation of innate and adaptive immunity, characterized by lipid deposition, leukocyte infiltration and proliferation of vascular smooth muscle cells. Subcli...

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  • publication . Article . Other literature type . 2018
    Open Access Russian
    Authors:
    Karateev, A. E.; Nasonov, E. L.; Ivashkin, V. T.; Martynov, A. I.; Yakhno, N. N.; Arutyunov, G. P.; Alekseeva, L. I.; Abuzarova, G. R.; Evseev, M. A.; Kukushkin, M. L.; ...
    Persistent Identifiers
    Publisher: IMA-PRESS LLC

    In 2015, the experts from various medical associations of Russia elaborated the clinical guidelines “Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice”. These guidelines were drawn up to improve the use of NSAIDs, our country’s most popu...

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16 research outcomes, page 1 of 2