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The aim of the study was to analyze and summarize available literature data on the role of autophagy in thyroid cancer. Material and methods. We analyzed 34 publications available from pubmed and elibrary. Ru databases concerning thyroid cancer and autophagy. Results. T...

Abstract. Breast cancer is one of the most commonly diagnosed cancers worldwide. According to the World Health Organization, the incidence of breast cancer was 2.26 million in 2020, overtaking the incidence of lung cancer. In Russian Federation, the increase in new case...

Aim of the study: to evaluate the results of using intraoperative radiotherapy (IO RT) in patients with locally advanced rectal cancer (RC).Material and Methods. A total of 172 patients with histologically confirmed stage II –III (pT3–4 or pN+) RC were included in this ...

The aim of the study was to analyze the most significant studies representing the basic principles of diagnosis and treatment of patients with breast cancer (BC) during the CO VID -19 pandemic.Material and Methods. The search for relevant sources was carried out in PubM...

Modern tissue engineering approaches are aimed at developing scaffolds that contribute to the development of the whole variety of intercellular interactions that imitate those in a real object.The purpose of the study was to collect and summarize the data on the creatio...

The humanization of immunodeficient animals allows us to study the growth of xenografts of human malignant tumors and their response to therapeutic effects, taking into account processes in the immune system and tumor zone, which have a significant impact on oncogenesis...

The purpose of the study was to evaluate the efficacy and safety of laparoscopic transgastric resection for mesenchymal tumors of the proximal stomach.Material and Methods. A retrospective-prospective study was carried out. Surgical techniques of laparoscopic transgastr...

Introduction. High incidence and mortality rates of colorectal cancer indicate an urgent need for the use of new highly specific diagnostic and prognostic molecular markers. In this aspect, cancer testis antigens (CTA s) are of particular interest.The aim of the study w...

Background. Heat stress (HS) induces the cellular secretion of heat shock proteins (HSP ) and extracellular nanovesicles (ENVs). The biological link between these phenomena is poorly understood. In the case of colorectal cancer (CRC) cells, the secretion of HSP s and EN...

Aim. To assess the possibility of using empirical models for predicting a second metachronous tumor after chemotherapy of the first one to improve the efficiency of prophylactic medical examination of cancer patients.Material and Мethods. The objects of the study are el...