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  • Publication . Preprint . Article . 2021 . Embargo End Date: 01 Jan 2021
    Open Access
    Authors: 
    de Vilmarest, Joseph; Goude, Yannig;
    Publisher: arXiv
    Country: France

    We present the winning strategy of an electricity demand forecasting competition. This competition was organized to design new forecasting methods for unstable periods such as the one starting in Spring 2020. We rely on state-space models to adapt standard statistical a...

  • Publication . Preprint . Article . 2021
    English
    Authors: 
    Nakamura, Gilberto M.; Plaszczynski, Stéphane; Grammaticos, Basile; Badoual, Mathilde;
    Publisher: HAL CCSD
    Country: France

    International audience; We study the effect of an emerging virus mutation on the evolution of an epidemic, inspired by the appearance of the delta variant of SARS-CoV-2. We show that if the new variant is markedly more infective than the existing ones the epidemic can r...

  • Publication . Preprint . Article . 2021
    Open Access
    Authors: 
    Célia Caillet-Saguy; Nicolas Wolff;
    Publisher: MDPI AG
    Country: France

    AbstractAngiotensin converting enzyme 2 (ACE2) is a main receptor for SARS-CoV-2 entry to the host cell. Indeed, the first step in viral entry is the binding of the viral trimeric spike protein to ACE2. Abundantly present in human epithelial cells of many organs, ACE2 i...

  • Open Access English
    Authors: 
    Cédric Gil-Jardiné; Gabrielle Chenais; Catherine Pradeau; Eric Tentillier; Philipe Revel; Xavier Combes; Michel Galinski; Eric Tellier; Emmanuel Lagarde;
    Country: France

    Abstract Objectives During periods such as the COVID-19 crisis, there is a need for responsive public health surveillance indicators related to the epidemic and to preventative measures such as lockdown. The automatic classification of the content of calls to emergency ...

  • Open Access
    Authors: 
    José Miguel Urra; Elisa Ferreras-Colino; Marinela Contreras; Carmen M. Cabrera; Isabel G. Fernández de Mera; Margarita Villar; Alejandro Cabezas-Cruz; Christian Gortázar; José de la Fuente;
    Publisher: BioRxiv
    Country: Spain

    The coronavirus disease 19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide. The characterization of the immunological mechanisms involved in disease symptomatology and protective respon...

  • Open Access English
    Authors: 
    Andrew E. Clark; Conchita D'Ambrosio; Anthony Lepinteur;
    Publisher: HAL CCSD
    Countries: Luxembourg, France

    We here use panel data from the COME-HERE survey to track income inequality during COVID-19 in France, Germany, Italy, and Spain. Relative inequality in equivalent household disposable income among individuals changed in a hump-shaped way between January 2020 and Januar...

  • Open Access
    Authors: 
    Antoine Rebendenne; Priyanka Roy; Boris Bonaventure; Ana Luiza Chaves Valadão; Lowiese Desmarets; Yves Rouillé; Marine Tauziet; Mary Arnaud-Arnould; Donatella Giovannini; Yenarae Lee; +10 more
    Publisher: Cold Spring Harbor Laboratory

    Several genome-wide CRISPR knockout screens have been conducted to identify host factors regulating SARS-CoV-2 replication, but the models used have often relied on overexpression of ACE2 receptor. Additionally, such screens have yet to identify the protease TMPRSS2, kn...

  • Open Access
    Authors: 
    Dominique Grandjean; Capucine Gallet; Clothilde Lecoq-Julien; Riad Sarkis; Quentin Muzzin; Vinciane Roger; Didier Roisse; Nicolas Dirn; Clement Levert; Erwan Breton; +21 more
    Publisher: Cold Spring Harbor Laboratory

    ABSTRACT Facing the COVID-19 pandemic, testing individuals in order to promptly isolate positive people is one of the key actions. One approach to rapid testing might be to consider the olfactory capacities of trained detection dogs in order to develop a non-invasive, r...

  • Open Access
    Authors: 
    Allenbach, Yves; Saadoun, David; Maalouf, Georgina; Vieira, Matheus; Hellio, Alexandra; Boddaert, Jacques; Gros, Helene; Salem, Joe Elie; Resche-Rigon, Matthieu; Biard, Lucie; +2 more
    Publisher: Cold Spring Harbor Laboratory

    AbstractBackgroundPrognostic factors of coronavirus disease 2019 (COVID-19) patients among European population are lacking. Our objective was to identify early prognostic factors upon admission to optimize the management of COVID-19 patients hospitalized in a medical wa...

  • Open Access
    Authors: 
    Ortega, Maria Ruiz; Spisak, Natanael; Mora, Thierry; Walczak, Aleksandra M.;
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | STRUGGLE (724208)

    Adaptive immunity’s success relies on the extraordinary diversity of protein receptors on B and T cell membranes. Despite this diversity, the existence of public receptors shared by many individuals gives hope for developing population wide vaccines and therapeutics. Ye...