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contribution à un site web; Several countries in the Western Balkans have responded to the Covid-19 outbreak with draconian measures that entail a further erosion of democracy, writes Natasha Wunsch. She argues the pandemic is shining a spotlight on the impact of geopolitical competition in the Western Balkans, where authoritarian forces are undermining the EU’s democracy promotion efforts.

What is the future of technocracy, after COVID-19, asks Jonathan White (LSE)? Current crisis management only blurs ever more the boundary between politics and technical expertise, he argues.

COVID-19 has decimated livelihoods in urban India and created a new underclass of workers who are being pushed into poverty. Shania Bhalotia, Swati Dhingra and Fjolla Kondirolli (LSE) say a national work guarantee is needed to prevent mass long-term unemployment and poverty.

Problems of this severity and scope can only be solved through global cooperation, write Muhammad Shahbaz and Muhammad Ali Nasir

California’s ‘superstar’ cities and regions – which together make up nearly 90 percent of the state’s GDP – have experienced the highest number of COVID-19 cases. Maliha Ahmed writes that despite being hard hit, these superstar areas have a combination of industries which have been less affected by the pandemic compared to those in poorer areas. With both superstar and non-superstar areas experiencing nearly equal increases in unemployment since February, she argues that policymakers will need to target assistance to poorer areas to prevent rising inequality.

The thirteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) Laboratories Annual Workshop took place on the 28-30 April 2022 in Weggis, Switzerland and focused on methods in mammary gland biology and breast cancer. Sixty scientists participated in the ENBDC annual workshop which had not been held in person since 2019 due to the global COVID-19 pandemic. Topics spanned the mammary gland biology field, ranging from lactation biology and embryonic development, single cell sequencing of the human breast, and stunning cutting-edge imaging of the mouse mammary gland and human breast as well as breast cancer research topics including invasive progression of the pre-invasive DCIS stage, metabolic determinants of endocrine therapy resistance, models for lobular breast cancer, and how mutational landscapes of normal breast during age and pregnancy determine cancer risk. The latest findings from participating researchers were presented through oral presentations and poster sessions and included plenty of unpublished work.

Despite the overall drop in COVID-19 deaths, the latest data reveal continuing increases occurring in care homes and the community. Melanie Henwood explains why there is a need for more scrutiny around what is happening in care homes and across the social care system.

Adjusting for population size and agreeing on the definition of a 'Covid death' can have important policy implications, writes Neil Monnery

OBJECTIVES: To describe the serological profile of first two SARS-CoV-2 confirmed reinfections in the national healthcare worker cohort study SARS-CoV-2 Immunity and Reinfection Evaluation (SIREN) and potentially identify correlates of protection against reinfection. METHODS: In addition to routine testing within the SIREN study, viral culture, sequencing and phylogenetic analysis were performed. Total antibody testing (Anti-SARS-CoV-2 nucleocapsid and Anti-SARS-CoV-2 spike) were complemented by receptor binding domain indirect ELISA and neutralising antibody assays. RESULTS: The first two SARS-CoV-2 confirmed reinfections had mild symptomatic illness episodes from which infectious virus was recovered at the time of reinfection. The recovered viruses and their sequences were closely related to viruses circulating locally during the time of reinfection and serology was consistent with reinfection. Prior to reinfection, both cases had ELISA and immunoblot detectable anti-N antibodies, but lacked live virus neutralising antibody. Within days following reinfection, neutralising antibodies became detectable and anti-N and anti-S binding antibodies were boosted. CONCLUSIONS: We hypothesise that titres of neutralising antibody can be used as a correlate of protection against reinfection. Further analysis using a case-control design is essential in order to confirm this hypothesis.