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The numerical simulations evolve more and more to simulations of complex physical phenomena through multi-scale or multi-physics codes. For these kind of simulations data analysis is a main issue for many reasons, as detecting bugs during the development phase or to und...

My PhD is in the frame of the comparative oncology field about the genetic study of mucosal melanoma (MM) in dogs, that spontaneously develop oral melanoma, frequent in some breed and severe. Thus, it constitutes a good natural model for human MM that is rare and very a...

Ligninolytic fungi are wood-degrading organisms that use cellulose, hemicelluloses, and lignin as sources of carbon and energy. However, the oxidative processes used by these fungi to decompose wood release a myriad of potentially toxic extractable molecules. These extr...

Soft chemistry is attractive thanks to its easy implementation. However, the related phenomena are poorly understood to this day. Usually, crystal size and their nucleation rate are described using classical nucleation theories. By construction, they neglect (i) any pot...

In this thesis we used dynamical systems methods and numericalsimulations to study the mechanisms of epileptic oscillations associated with ionconcentration changes and cerebellar Purkinje cell bimodal behavior. The general issue in this work is the interplay between si...

Cerebellar defects encompass a group of rare diseases affecting cerebellar functioning. The prevalence of these defects is estimated to be 26 in 10000 children in Europe. These diseases lead to movement disorders (ataxia) and are frequently associated with intellectual ...

South Greenland is a key region placed under Arctic and Northern Atlantic influences, whichis poorly documented in terms of atmospheric monitoring. The aim of my thesis is to conductand use the first regional atmospheric observations of CO2, O2, CH4 and isotopic composi...

This thesis addresses the problem where a team of cooperative and autonomous agents, working in a stochastic and partially observable environment towards solving a complex task, needs toe dynamically modify its structure during the process execution, so as to adapt to t...

This work aims to analyze six weeks of videoconferenced pedagogical interaction betweentrainee teachers enrolled in a master's degree in teaching French as a foreign language (FLE)at a French university (Lyon 2) and learners of French at a foreign university (Dublin Cit...

Approximate Numerical Expressions (ANE) are imprecise linguistic expressions implying numerical values, illustrated by "about 100". We first focus on ANE interpretation, both in its human and computational aspects. After defining original arithmetical and cognitive dime...