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2,714 research outcomes, page 1 of 272
  • publication . Article . 2014
    Closed Access
    Authors:
    Pietro Enea Lazzerini; Pier Leopoldo Capecchi; Maurizio Acampa; Mauro Galeazzi; Franco Laghi-Pasini;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract When compared to the general population, patients with rheumatoid arthritis (RA) have an overall standard mortality ratio of approximately two, with more than 50% of premature deaths attributable to cardiovascular disease (CVD). Moreover, RA patients were twice...

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  • publication . Article . 2014
    Closed Access
    Authors:
    Lazaros I. Sakkas; Dimitrios P. Bogdanos; Christina G. Katsiari; Chris D. Platsoucas;
    Persistent Identifiers
    Publisher: Elsevier BV

    Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the presence of rheumatoid factor (RF) and anti-citrullinated protein/peptide autoantibodies (ACPAs). Citrulline derives from arginine by peptidyl arginine deiminases, and ACPAs are directed agai...

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  • publication . Article . Other literature type . 2009
    Open Access
    Authors:
    J. A. Solís Herruzo; P. Solís Muñoz; T. Muñoz Yagüe;
    Publisher: Elsevier BV

    Primary biliary cirrhosis (PBC) would develop when the immune system comes across a microorganism with proteins similar to those in the piruvate dehydrogenase complex E2 (PDC-E2), or a neoantigen resulting from a xenobiotic-modified autoantigen. This would lead to an in...

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  • publication . Article . 2013
    Authors:
    Mariana Figueiroa Careta; Claudia da Costa Leite; Fernando Betty Cresta; Jose Albino; Mirian Tsunami; Ricardo Romiti;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Introduction Scleroderma featuring rare connective tissue disease that manifests as skin sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement and ...

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  • publication . Article . 2020
    Closed Access
    Authors:
    Keum Hwa Lee; Byung Soo Ahn; Dohyeon Cha; Won Woo Jang; Eugene Choi; Soo Hyun Park; Jun Hyeong Park; Junseok Oh; Da Eun Jung; Heeryun Park; ...
    Persistent Identifiers
    Publisher: Elsevier BV

    Autoimmune diseases are clinical syndromes that result from pathogenic inflammatory responses driven by inadequate immune activation by T- and B-cells. Although the exact mechanisms of autoimmune diseases are still elusive, genetic factors also play an important role in...

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  • publication . Article . 2015
    Closed Access
    Authors:
    Clodoveo Ferri; Andreina Teresa Manfredi; Marco Sebastiani; Michele Colaci; Dilia Giuggioli; Caterina Vacchi; Giovanni Della Casa; Stefania Cerri; Pietro Torricelli; Fabrizio Luppi;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Background Interstitial lung diseases (ILDs) are a heterogeneous group of disorders characterized by inflammation and/or fibrosis of the lungs, varying from idiopathic interstitial pneumonias to secondary variants, including the ILDs associated to connective ti...

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  • publication . Article . 2019
    Closed Access English
    Authors:
    L. Delaval; Aurélie Daumas; Maxime Samson; Mikael Ebbo; Hubert de Boysson; Eric Liozon; Henry Dupuy; Mathieu Puyade; Daniel Engelbert Blockmans; Ygal Benhamou; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    Abstract Background Age at onset of large-vessel vasculitis (LVV) is commonly used to distinguish giant cell arteritis (GCA) and Takayasu arteritis (TA). However, LVV between age 50 and 60 years may be difficult to classify. Methods We conducted a retrospective study in...

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  • publication . Article . 2002
    Closed Access
    Authors:
    Jorge Findor; Xiao-Song He; Juan Sord; Ruben Terg; M. Eric Gershwin;
    Persistent Identifiers
    Publisher: Elsevier BV

    The findings by epidemiological studies on the link between PBC and HCC are in general agreement with the notion that cirrhosis is a risk factor for HCC development. From the clinical perspective, this implies that in PBC patients with cirrhosis, the screening for HCC s...

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  • publication . Article . 2003
    Closed Access
    Authors:
    Philippe Krebs; Michael O. Kurrer; Ugur Sahin; Özlem Türeci; Burkhard Ludewig;
    Persistent Identifiers
    Publisher: Elsevier BV

    Autoantibodies can be detected in autoimmune diseases with a long prodromal phase and may serve as early indicators of disease activity. Autoantibody-based screening methods are therefore potent tools for the identification of target antigens. The SEREX method (serologi...

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  • publication . Article . 2011
    Closed Access
    Authors:
    Yael Eshet; Rachel Pauzner; Orly Goitein; Pnina Langevitz; Iris Eshed; Chen Hoffmann; Eli Konen;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Introduction MRI and MRA are used for diagnosis and activity determination of patients with Takayasu's arteritis (TA). However, there is a limited experience regarding the role of MRI in long-term follow-up of those patients. The aim of the present study was to...

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2,714 research outcomes, page 1 of 272