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  • Open Access
    Authors: 
    Smolikhina, P.M.; Muratova, E.I.; Dvoretsky, S.I.; Tambov State Technical University; Tambov State Technical University; Tambov State Technical University;
    Publisher: Tambov State Technical University

    The article is devoted to the complex study of the rheological properties of raw materials, semi-finished and finished products to support optimal modes of production and to manufacture products with specified structural-mechanical characteristics. It was found that the...

  • Open Access
    Authors: 
    Michitaka Kono; Shigeaki Aoyagi; Teiji Okazaki; Keiichiro Tayama;
    Publisher: International Heart Journal (Japanese Heart Journal)

    Sjogren's syndrome (SS) is an autoimmune disease characterized by dryness of the mouth and the eyes. Systemic involvement in SS is well known, however, obvious cardiac manifestations, particularly significant valve disorders, are extremely rare and only three cases of s...

  • Closed Access
    Authors: 
    Shu-jun Shan; Jun Luo; Deran Xu; Xingliang Niu; Ding-qiao Xu; Panpan Zhang; Ling-Yi Kong;
    Publisher: Elsevier BV

    Abstract Ginkgo biloba L. is a widely used medicinal plant that has a high concentration of its bioactive components, flavonoids and ginkgolides, in its leaves. Gingko seeds are also consumed as a functional food and medicine throughout the world to slow the ageing proc...

  • Closed Access
    Authors: 
    Kirstie L. Haywood; Laura Whitehead; Gavin D. Perkins;
    Publisher: Elsevier BV

    Few people would argue with the importance of survival as an outcome of cardiac arrest. However, once patients have ‘survived’, the quality of that survival in both the short and long-term is important. Although a range of perspectives are helpful, that of the patient i...

  • Publication . Article . 2015
    Closed Access
    Authors: 
    Sharon Bradley-Johnson; C. Merle Johnson; Daniel D. Drevon;
    Publisher: SAGE Publications

    Students with low-incidence disabilities frequently receive less than optimal psychoeducational services because the specialized tests and instructional materials required to meet their idiosyncratic needs often are unavailable due to budget constraints, inadequate tra...

  • Closed Access
    Authors: 
    Regina Taurines; Mònica Segura; Martin Schecklmann; Laura Albantakis; Edna Grünblatt; Susanne Walitza; Thomas Jans; Benjamin Lyttwin; Michael Haberhausen; Frank M. Theisen; +6 more
    Publisher: Springer Science and Business Media LLC

    Findings from molecular genetic studies and analyses of postmortem and peripheral tissue led to the hypothesis that neurotrophins—as crucial moderators of neuroplasticity—impact on the pathophysiology of autism spectrum disorder (ASD). The study projects aimed to comple...

  • Open Access English
    Authors: 
    Stefan Holderbach; Stefan Holderbach; Lukas Adam; Lukas Adam; B. Jayaram; Rebecca C. Wade; Rebecca C. Wade; Rebecca C. Wade; Goutam Mukherjee; Goutam Mukherjee;
    Publisher: Frontiers Media S.A.

    The virtual screening of large numbers of compounds against target protein binding sites has become an integral component of drug discovery workflows. This screening is often done by computationally docking ligands into a protein binding site of interest, but this has t...

  • Open Access
    Authors: 
    Anastasia A. Bebenina; Madina A. Chundokova; Alexey N. Smirnov; Maxim A. Golovanev; Alina A. Dokshukina;
    Publisher: Paediatrician Publishers LLC

    Background. KID syndrome (keratitis-ichthyosis-deafness) is an orphan genetic multisystem disease with autosomal recessive and dominant types of inheritance, it manifests in the neonatal period. The leading triad of symptoms is: skin lesions, ophthalmological diseases a...

  • Closed Access
    Authors: 
    Dewanjee, Saikat; Gangopadhyay, Moumita; Das, Urmi; Sahu, Ranabir; Samanta, Amalesh; Banerjee, Pamela;
    Publisher: Elsevier BV

    This study aimed to improve rosmarinic acid (RA) production in the whole plant culture of Solenostemon scutellarioides through elicitation with phytopathogenic fungi. Amongst selected fungi, Aternaria alternata caused significant elevation (p<0.05-0.01) in RA accumulati...

  • Open Access
    Authors: 
    Yoshiro Nakahara; Yukio Hosomi; Makoto Saito; Masumi Ogawa; Tsunekazu Hishima; Tatsuru Okamura; Jiichiro Sasaki; Noriyuki Masuda;
    Publisher: Spandidos Publications

    Little is known on the efficacy of erlotinib treatment in patients expressing wild-type epidermal growth factor receptor (EGFR). This study is a retrospective review of patients with non-squamous, non-small-cell lung cancer (NS-NSCLC) and wild-type EGFR who were treated...

  • Authors: 
    Makarov, Anton S.; Merkushev, Anton A.; Uchuskin, Maxim G.; Trushkov, Igor V.;
    Publisher: American Chemical Society (ACS)

    Oxidative rearrangement of 2-(2-aminobenzyl)furans affording 2-(2-acylvinyl)indoles in a stereocontrolled manner in good-to-excellent yields has been developed. Thus, (2-aminobenzyl)furans with electron-releasing alkoxy substituents in the phenyl group form only E-isome...

  • Closed Access
    Authors: 
    Eugenio Ferrario; Riccardo Miggiano; Menico Rizzi; Davide M. Ferraris;
    Publisher: International Union of Crystallography (IUCr)

    L-Hydroxyproline (L-Hyp) is a nonstandard amino acid that is present in certain proteins, in some antibiotics and in the cell-wall components of plants. L-Hyp is the product of the post-translational modification of protein prolines by prolyl hydroxylase enzymes, and th...

  • Closed Access
    Authors: 
    Ang Chee Wei; Mohamed Ashraf Ali; Yeong Keng Yoon; Sy Bing Choi; Hasnah Osman; Vijay H. Masand; Tan Soo Choon;
    Publisher: Springer Science and Business Media LLC

    Two series of novel and highly functionalised dispiropyrrolidines were synthesized using 1,3-dipolar cycloaddition reaction. The synthesized compounds were screened for their antimycobacterial activity against M. tuberculosis H37Rv using the Promega reagent BacTiter-Glo...

  • Open Access
    Authors: 
    Carol A. Rowley; Amber B. Sauder; Melissa M. Kendall;
    Publisher: American Society for Microbiology

    Enteric pathogens exploit chemical and nutrient signaling to gauge their location within a host and control expression of traits important for infection. Ethanolamine-containing molecules are essential in host physiology and play important roles in intestinal processes....

  • Open Access English
    Authors: 
    Blázquez-Blázquez, Enrique; Pérez, Ernesto; Lorenzo, Vicente; Cerrada, María L.;
    Publisher: Multidisciplinary Digital Publishing Institute
    Country: Spain
    Project: EC | CALIPSO (312284)

    Blends of poly(ε-caprolactone) (PCL) and high-density polyethylene (HDPE) have been prepared at different compositions in order to assess the effect of HDPE on gas transport and mechanical behaviors of PCL. Previous to this evaluation, a complete morphological, structur...

  • Closed Access
    Authors: 
    Susan Oliver; Thi Thu Phuong Pham; Yang Li; Fu-Jian Xu; Cyrille Boyer;
    Publisher: Royal Society of Chemistry (RSC)

    Skin, the largest organ in the human body, provides several important functions, including providing protection from mechanical impacts, micro-organisms, radiation and chemicals; regulation of body temperature; the sensations of touch and temperature; and the synthesis ...

  • Closed Access
    Authors: 
    R. Patejdl; A.‐C. Leroux; T. Noack;
    Publisher: Wiley

    Background Phenytoin is widely used as a second-line treatment for status epilepticus. Besides its well-known cardiac pro-arrhythmogenicity, side effects on other organ systems have received less attention. Methods This study investigates the effects of phenytoin on gas...

  • Open Access
    Authors: 
    Takamasa Numano; Jiegou Xu; Mitsuru Futakuchi; Katsumi Fukamachi; David B. Alexander; Fumio Furukawa; Jun Kanno; Akihiko Hirose; Hiroyuki Tsuda; Masumi Suzui;
    Publisher: Asian Pacific Organization for Cancer Prevention

    Two types of nanosized titanium dioxide, anatase (anTiO2) and rutile (rnTiO2), are widely used in industry, commercial products and biosystems. TiO2 has been evaluated as a Group 2B carcinogen. Previous reports indicated that anTiO2 is less toxic than rnTiO2, however, u...

  • Open Access
    Authors: 
    Yong Yang; Han Cheng; Hui Yan; Peng Zhan Wang; Rong Rong; Yingying Zhang; Cheng Bo Zhang; Rui kun Du; Li Jun Rong;
    Publisher: Wiley

    Emerging viruses such as Ebola virus (EBOV), Lassa virus (LASV), and avian influenza virus H5N1 (AIV) are global health concerns. Since there is very limited options (either vaccine or specific therapy) approved for humans against these viruses, there is an urgent need ...

  • Open Access
    Publisher: Publishing House Belorusskaya Nauka

    In a neutral medium, the exposure of thiamine disulfide to the ultraviolet of solar radiation (as well as to the ultraviolet radiation of mercury lamp with λ &gt; 300 nm) results in the formation of a thiamine molecule with closed thiazole ring and a molecule of thiamin...

  • Authors: 
    Ming-Ying Hsu; Shenq-Tsong Chang; Ting-Ming Huang;
    Publisher: SPIE

    The position of the projection lens in a lens mount needs to be fixed using bolts in the alignment process. The lens mount is need bolts to fix lens in correct position. The bolt joint stress causes the mount and lens to deform. The bolt's number increase can help the b...

  • Open Access
    Authors: 
    Yuichiro Shindo; Yoshinori Hasegawa;
    Publisher: Wiley

    Antibiotic resistance is of great concern for both infection control and the treatment of infectious diseases. Previous studies reported that the occurrence of drug-resistant pathogens (DRPs)-for instance, methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas ...

  • Open Access
    Authors: 
    Gregory C. Donohoe; Mahdiar Khakinejad; Stephen J. Valentine;
    Publisher: American Chemical Society (ACS)

    Ion mobility spectrometry (IMS) coupled with hydrogen deuterium exchange (HDX)-mass spectrometry (MS) has been used to study the conformations of negatively-charged peptide and protein ions. Results are presented for ion conformers of angiotensin 1, a synthetic peptide ...

  • Closed Access
    Authors: 
    Bernd Schmidt; Martin Riemer;
    Publisher: Wiley

    Magnaldehydes B and E along with their 4'-methylated derivatives are naturally occurring 2,4'-biphenols that have been isolated from the Magnoliaceae. Herein, these natural products have been synthesized from a common intermediate, which was obtained by a microwave-prom...

  • Closed Access
    Authors: 
    Mohammad Firdaus Abu Hashim; Mohd Mustafa Al Bakri Abdullah; Che Mohd Ruzaidi Ghazali; Kamarudin Hussin; Muhammad Faheem Mohd Tahir; Mohammed Binhussain;
    Publisher: Trans Tech Publications, Ltd.

    In this study, the effect of geopolymer materials in epoxy hardener was studied under mechanical testing which is using flexural test. A series of epoxy filled with 10%-30% weight percentage geopolymer materials which are white clay, fly ash and silica sand was prepared...

  • Open Access
    Authors: 
    Trujillo, James P.; Gerrits, Niels J.H.M.; Vriend, Chris; Berendse, Henk W.; van den Heuvel, Odile A.; van der Werf, Ysbrand D.;
    Country: Netherlands

    Abstract Objective Parkinson's disease (PD) often entails impairments of executive functions, such as planning. Although widely held that these impairments arise from dopaminergic denervation of the striatum, not all executive functions are affected early on, and the un...

  • Closed Access
    Authors: 
    Seiichi Matsugo; Hironori Sugiyama; Yuki Nishimoto; Hirofumi Misu; Toshinari Takamura; Shuichi Kaneko; Yukari Kubo; Reina Saito; Kan Kanamori;
    Publisher: Elsevier BV

    Abstract Vanadium compounds are known to possess a variety of physiological actions, including insulin-mimetic activities. We synthesized two peroxidovanadium(V) complexes (pVs) having the amino acid derivative N -(4-imidazolylmethyl)- l -alanate (imala) or N -(4-imidaz...

  • Authors: 
    Xiong, J.; Kubo, K.; Noro, S.; Akutagawa, T.; Nakamura, T.;
    Publisher: (:unav)

    Four supramolecular cations (m-XAni+)(DB[18]crown-6) (X = F, Cl, Br or I; Ani+ = anilinium ion; DB[18]crown-6 = dibenzo[18]crown-6) were introduced into crystals of a Keggin [SMo12O402−] polyanion to form [(m-XAni+)(DB[18]crown-6)]2[SMo12O402−]·4CH3CN (1, 2, 3 or 4 for ...

  • Closed Access
    Authors: 
    Lipika Rani Bairi; C. Mallika; U. Kamachi Mudali;
    Publisher: Elsevier BV

    Metal waste form (MWF) alloys of composition D9SS–8.5Zr, D9SS–10Zr–1NMFP and D9SS–10Zr–1NMFP–10U were prepared by casting of D9SS (Ti-modified austenitic 316 stainless steel), zirconium, NMFPs (noble metal fission products) and uranium for evaluating the influence of NM...

  • Authors: 
    Chun‐Ru Cao; Song Ou; Min Jiang; Jin-Tao Liu;
    Publisher: Royal Society of Chemistry (RSC)

    A series of tetrasubstituted fluoroalkene derivatives were synthesized by the reaction of α-fluoro-β-carbonyl benzothiazol-2-yl sulfones with various nucleophiles in good yields with high stereoselectivities. The predominant cis configuration of fluorine and alkynyl gro...

  • Open Access
    Authors: 
    Glen Davison; Jade Dyer; Samuele Maria Marcora; Alexis R. Mauger;
    Publisher: Cambridge University Press (CUP)

    Osteoarthritis (OA) is a group of chronic, painful, disabling conditions affecting synovial joints where the pathology includes damage and loss of articular cartilage, irregular remodelling and erosion of sub-articular bone, synovial distension and inflammation(1). Whil...

  • Closed Access
    Authors: 
    Ahmareen Baten; Masoom Desai; Miguel Melo-Bicchi; Camilo Gutierrez;
    Publisher: SAGE Publications

    Objective. Herpes simplex virus encephalitis (HSE) is the most common cause of sporadic fatal encephalitis worldwide and remains a devastating disease despite antiviral therapy. EEG can be an important tool in the diagnosis of HSE, and we propose that it can be used to...

  • Closed Access
    Authors: 
    N.A. de Oliveira; P.J. von Ranke; A. Troper;
    Publisher: Elsevier BV

    Abstract In this paper we theoretically discuss the magnetocaloric effect in ( Tb c R 1 - c ) Co 2 (R = Er and Ho). To this end, we use a model Hamiltonian in which are included the 4 f electrons from rare earth ions and the 3 d electrons from Co ions. In the model is a...

  • English
    Authors: 
    Nga-Thi-Thanh Trinh; Raja Lejmi; Adem Gharsallaoui; Emilie Dumas; Pascal Degraeve; Mai Le Thanh; Nadia Oulahal;
    Publisher: HAL CCSD
    Country: France

    Spray-dried redispersible transcinnamaldehyde (TC)-in-water emulsions were prepared in order to preserve its antibacterial activity; 5% (w/w) TC emulsions were first obtained with a rotor-stator homogeniser in the presence of either soybean lecithin or sodium caseinate ...

  • Publication . Article . Other literature type . 2013
    Open Access
    Authors: 
    de Jonge, Pieter Jan F; van Blankenstein, Mark; Grady, William M; Kuipers, Ernst J;
    Country: Netherlands

    Although endoscopic surveillance of patients with Barrett's oesophagus has been widely implemented, its effectiveness is debateable. The recently reported low annual oesophageal adenocarcinoma risk in population studies, the failure to identify most Barrett's patients a...

  • Open Access English
    Authors: 
    Jia You Lin; Bao Rong Juo; Yu Hsuan Yeh; Shu Hsuan Fu; Yi-Ting Chen; Chien Lun Chen; Kun Pin Wu;
    Publisher: BMC

    Abstract Background Early detection of bladder cancer remains challenging because patients with early-stage bladder cancer usually have no incentive to take cytology or cystoscopy tests if they are asymptomatic. Our goal is to find non-invasive marker candidates that ma...

  • Open Access English
    Authors: 
    Isabel J. Hoppe; Hans Brandstetter; Esther Schönauer;
    Publisher: Nature Publishing Group UK

    AbstractCollagen is the most abundant protein in higher animals and as such it is a valuable source of amino acids and carbon for saprophytic bacteria. Due to its unique amino acid composition and triple-helical tertiary structure it can however only be cleaved by speci...

  • Publication . Article . 2016
    Open Access English
    Authors: 
    Alberto Toscano;
    Publisher: Duke University Press
    Country: United Kingdom

    This article revisits the problematic of the cognitive mapping of capital by probing the affinity between two representational predicaments: the depopulated nature of images of human-altered landscapes in the “new topographics” photography and its epigones, and the curr...

  • Open Access
    Authors: 
    Moriya, Jun; Tanino, Mishie Ann; Takenami, Tomoko; Endoh, Tomoko; Urushido, Masana; Kato, Yasutaka; Wang, Lei; Kimura, Taichi; Tsuda, Masumi; Nishihara, Hiroshi; +2 more
    Publisher: Springer Science and Business Media LLC

    The role of intraoperative pathological diagnosis for central nervous system (CNS) tumors is crucial for neurosurgery when determining the surgical procedure. Especially, treatment of carmustine (BCNU) wafers requires a conclusive diagnosis of high-grade glioma proven b...

  • Authors: 
    Luis Hernandez; Tereza Lanitis; C Cele; H Toro-Diaz; Andrea Gibson; Andreas Kuznik;
    Publisher: Academy of Managed Care Pharmacy

    BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of vision loss in the United States. The most severe vision loss occurs in patients with neovascular AMD, known as wet AMD (wAMD). The most commonly used antivascular endothelial growth factor (VEGF...

  • Open Access English
    Authors: 
    Sandra Schönburg; Petra Anheuser; Jennifer Kranz; Paolo Fornara; Viktor Oubaid;
    Publisher: Springer London

    AbstractThe rapid rise of robotic-assisted surgery (RAS) has necessitated an efficient and standardized training curriculum. Cognitive training (CT) can significantly improve skills, such as attention, working memory and problem solving, and can enhance surgical capacit...

  • Authors: 
    Sultan, Anas M.; Hughes, Zak E.; Walsh, Tiffany R.;
    Publisher: American Chemical Society (ACS)

    Despite the extensive utilization of biomolecule–titania interfaces, biomolecular recognition and interactions at the aqueous titania interface remain far from being fully understood. Here, atomistic molecular dynamics simulations, in partnership with metadynamics, are ...

  • Open Access
    Authors: 
    Stefan H. E. Kaufmann; B Bloom; Roland Brosch; P-J Cardona; Hazel M. Dockrell; Bernard Fritzell; Leander Grode; Willem A. Hanekom; David A. Hokey; Michael Levin; +10 more
    Country: Switzerland
    Project: SNSF | Tuberculosis - Protein Se... (31003A_153349)

    AbstractOn July 9, 2014, Aeras and the Max Planck Institute for Infection Biology convened a workshop entitled “Whole Mycobacteria Cell Vaccines for Tuberculosis” at the Max Planck Institute for Infection Biology on the grounds of the Charité Hospital in Berlin, Germany...

  • Open Access
    Authors: 
    Watcharakorn Mongkol; Wang Nguitragool; Jetsumon Sattabongkot; Anchanee Kubera;
    Publisher: Wiley

    Malaria parasites are transmitted through blood feeding by female Anopheline mosquitoes. Unveiling the blood-feeding process will improve understanding of vector biology. Anopheles dirus (Diptera: Culicidae) is one of the primary malaria vectors in the Greater Mekong Su...

  • Authors: 
    N. Venkatesham; K. Rajendar Reddy; Kamatala Chinna Rajanna; P. Veerasomaiah;
    Publisher: Informa UK Limited

    Vanadium pentoxide is used as an efficient catalyst for regioselective nitration of aromatic compounds under conventional and nonconventional conditions such as ultrasonically assisted (USAR) and microwave-assisted reactions (MWAR). The reactions underwent smoothly and ...

  • Open Access
    Authors: 
    Avni Berisha; Fetah I. Podvorica; Valbonë Mehmeti; Fidan Syla; Debatik Vataj;
    Publisher: Society of Chemists and Technologists of Macedonia

    &lt;p&gt;The corrosion behavior of iron in diluted aqueous sulfuric acid medium has been studied in the presence and absence of 6-ethoxybenzo[&lt;em&gt;d&lt;/em&gt;]thiazol-2-amine (EBT), 5-bromothiazol-2-amine (BTA) and 4,5-dimethylthiazol-2-amine (DTA). Potentiodynami...

  • Open Access English
    Authors: 
    Salam A.H. Al-Ameri; Mahmoud Najim Al-Jibouri; Taghreed Mohyaldeen Musa;
    Publisher: Elsevier

    Abstract A new Schiff base (HL) derived from condensation of p-anisidine and acetyl acetone has been prepared and used as a chelating ligand to prepare Cr(III), Mn(II), Co(II), Ni(II) and Cu(II) complexes. The study of the nature of these complexes formed in ethanol sol...

  • Publication . Article . 2014
    Closed Access
    Authors: 
    Lorenz Weidhase; H. Hentschel; L. Mende; G. Schulze; Sirak Petros;
    Publisher: Springer Science and Business Media LLC

    Acute poisoning is one of the more frequent presentations in acute and emergency medicine. Poisoning with pharmaceuticals is predominantly observed in adults. A detailed medical history and an accurate clinical examination establish the basis for the diagnostics. Typica...

  • Closed Access
    Authors: 
    Seyeon Park; Eun Sook Ahn; Yunjoo Kim;
    Publisher: Wiley

    The identification of small vesicles released by many cell types as tools of intercellular communication is proposed. Here, we identify SH-SY5Y neuroblastoma-derived exosomes comprised of major histocompatibility complex II (MHC II), Hsp90 and flotillin-1. Our data also...

  • Open Access English
    Authors: 
    Weiwei Tang; Liu Zihao; Yang Tongxin; Hanjin Wang; Xiu-Feng Cao;
    Publisher: Dove Press

    Wei-Wei Tang,1 Zi-Hao Liu,2 Tong-Xin Yang,2 Han-Jin Wang,1 Xiu-Feng Cao2 1Department of General Surgery, 2Department of Surgical Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, People&amp;rsquo;s Republic of China Abstract: Esophageal can...