While some economists argued for macro-prudential regulation pre-crisis, the macro-prudential approach and its emphasis on endogenously created systemic risk have only gained prominence post-crisis. Employing discourse and network analysis on samples of the most cited s...

<jats:sec><jats:title>Objective</jats:title><jats:p>TGF-β2 (TGF-β, transforming growth factor beta), the less-investigated sibling of TGF-β1, is deregulated in rodent and human liver diseases. Former data from bile duct ligated and MDR2 knockout (KO) mouse models for hu...

Made available in DSpace on 2016-01-24T14:38:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-11-24. Added 1 bitstream(s) on 2016-01-31T13:38:47Z : No. of bitstreams: 1 WOS000346115400003.pdf: 2792159 bytes, checksum: 8375776fd4bad38675bf63c9017760b1 (MD5) Pfiz...

Although often depicted as rigid structures, proteins are highly dynamic systems, whose motions are essential to their functions. Despite this, it is difficult to investigate protein dynamics due to the rapid timescale at which they sample their conformational space, le...

Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with DN. In this study...

<jats:p>Abstract. The Gulf of Aqaba is an elongated basin (~180 x 20 km) with depths reaching 1850 m. It represents the southern segment of the Dead Sea Transform (DST), which is one of the largest transform fault zones in the world. The opening of Gulf of Aqaba is thou...

This special issue on Cell Stress and Cell Death is aimed at bringing together recent developments in the fields of cellular stress and cell death and, in particular, the interplay between cell stress responses and cell death. The special issue opens with a review by S....

Treating large bone defects represents a major challenge in traumatic and orthopedic surgery. Bone tissue engineering provides a promising therapeutic option to improve the local bone healing response. In the present study tissue biocompatibility, systemic toxicity and ...

Introduction: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known. Method: This study was carried out prospectively in the multinational EULAR Scleroderma Trial and ...

Background: IL28B gene polymorphism is the best baseline predictor of response to interferon alfa-based antiviral therapies in chronic hepatitis C. Recently, a new IFN-L4 polymorphism was identified as first potential functional variant for induction of IL28B expression...