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  • publication . Article . Other literature type . 2015
    Open Access English
    Maria Laura Martin; Enrico Velardi; Margaret O'Connor; Kevin P. O’Rourke; Shuichiro Takashima; Lukas E. Dow; Gillian Lawrence; Odette M. Smith; Edward E. S. Nieuwenhuis; Yuan-Hung Lo; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Regulation of the intesti... (5R01HL125571-03), NIH | Strategies to Enhance Lym... (5R01AI080455-02), NIH | IL-22 in epithelial regen... (1K08HL115355-01), NIH | Mucosal Immunity and Micr... (9R01AI100288-06A1), NIH | Investigating the role of... (1K99CA176376-01), EC | STROMA (289720), NIH | IL-22 in Thymic Regenerat... (5R01AI101406-02), NIH | Strategies to enhance imm... (5R01HL069929-12), NIH | MARROW TRANSPLANTATION IN... (5P01CA023766-14)

    Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. The intestinal stem cell (ISC) niche provides Wnt, Notch, and epidermal growth factor (EGF) signals supporting Lgr5+ crypt base columnar ISCs for normal epithelial ma...

1 research outcomes, page 1 of 1