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143 research outcomes, page 5 of 15
  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Tuguzbaeva, G. M.; Pavlov, V. N.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>The initiation of carcinoma progression is attributed to significant disorders in the synthesis of macromolecules that affect physiological processes in the epithelial cells of oral mucosa. It is known that the integrin family receptors are crucial for regenerat...

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  • publication . Article . Other literature type . 2018
    Open Access Russian
    Authors:
    Dergunova, Yu. A.; Podionov, V. V.; Bozhenko, V. K.; Kometova, V. V.; Dardyk, M. V.;
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>Despite the sufficient amount of data accumulated in the literature, there are still no factors, on the basis of which it would be possible to estimate the regional lymph nodes status in breast cancer with a high degree of accuracy. The review presents literatur...

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  • publication . Article . 2016
    Open Access
    Authors:
    I. B. Zborovskaya; S. A. Galetskiy; A. V. Komel’kov;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Lipid rafts are lateral assembles of cholesterol, sphingomyelin, glicosphingolipids and specific proteins within cell plasma membrane. These microdomains are involved into a number of important cellular processes including membrane rearrangement, protein internalization...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Villert, A. B.; Kolomiets, L. A.; Yunusova, N. V.;
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>The severe heterogeneity of ovarian carcinomas on the molecular genetic level is associated with the absence of specific markers of chemoresistance. At the same time, ascites is an attractive biomarker detection fluid because it is easily obtained. The review is...

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  • publication . Article . 2019
    Open Access Russian
    Authors:
    V. A. Kobliakov;
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>The basic characteristics of tumours are ability for invasiveness and metastasis. These properties are realized due to destruction of intercellular matrix caused with acidification of intercellular area stimulated with transition from tissue respiration to glyco...

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  • publication . Article . 2016
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Background. Increased expression of transforming growth factor beta-1 (TGF-β1) in malignant brain tumors promotes cancer cells survival enhancing their growth, migration, invasion, angiogenesis, immune system suppression. Objective is to study molecular mechanisms of TG...

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  • publication . Article . 2018
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Epigenetics is a science studying mechanisms of heritable changes in gene function that occur without a change in the DNA sequence. One of the most important marks of epigenetic misbalance of cell genome is an replication asynchrony of genes with biallelic expression. I...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    Hepatocellular carcinoma (HCC) is one of the most common types of liver cancer that is mainly diagnosed at advanced stages. Since molecular markers that are currently used in clinical practice are not sensitive enough for effective diagnosis of HCC, active search of new...

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  • publication . Article . 2020
    Open Access Russian
    Authors:
    D. V. Sorokin; O. E. Andreeva; E. I. Mikhaevich; Yu. Yu. Shchegolev; A. M. Scherbakov; M. V. Gudkova; M. A. Krasil’nikov;
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>The most effective treatment of the hormone-dependent breast cancer is based on the antiestrogens SERM and aromatase inhibitor treatment, however its efficiency is limited by the acquired resistance to the drugs.</jats:p><jats:p>Previously we have revealed the e...

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  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    A. S. Ilnitskaya; A. B. Danilova; I. A. Baldueva;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>The development of an antitumor vaccine based on autologous dendritic cells (DCs) for bladder cancer treatment is extremely relevant today due to the proven high immunological potency of this type of tumor. Vaccination with DCs-based drugs as a monotherapy or in...

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143 research outcomes, page 5 of 15