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143 research outcomes, page 4 of 15
  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Gareev, I. F.; Beylerli, O. A.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>MicroRNAs are a new class of small non-coding RNAs, a length of 18–22 nucleotides that play a decisive role as posttranscriptional regulators of gene expression. Due to the large number of genes, regulated microRNAs, microRNAs are involved in many cellular proce...

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  • publication . Article . Other literature type . 2019
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    This review is devoted to modern notions about autoantibodies (AAb) as one of classes of tumor biomarkers. Principles of humoral response by way of autoantibodies to different tumor-associated proteins in the process of malignant tumor progression are considered. During...

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  • publication . Article . 2016
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    Neuroendocrine tumors comprise the heterogeneous group of malignant epithelial neoplasms, the diagnosis of which is based on their histopathologic features and immunohistochemical profile. For neuroendocrine tumors of the digestive system in the World Health Organizatio...

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  • publication . Article . 2017
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Tamoxifen is the drug of choice for endocrine therapy of hormone receptor- positive breast cancer in women in the reproductive period.  The metabolic activity of tamoxifen is determined by the activity of the enzyme CYP2D6, encoded by the gene of the same name: under  t...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    The modern concept of therapy for intrahepatic cholangiocarcinoma including surgical treatment, must take into account the achievements of molecular biology and modern staging principles. A detailed understanding of the molecular genetic (genetic and epigenetic) disorde...

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  • publication . Article . 2020
    Open Access
    Authors:
    E. O. Ignatova; D. A. Seryak; M. Yu. Fedyanin; A. A. Tryakin; I. A. Pokataev; S. F. Menshikova; Yu. V. Vakhabova; M. S. Karbyshev; K. V. Smirnova; S. A. Tulyandin;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>Epstein–Barr virus (EBV) associated gastric carcinoma is a special form of gastric adenocarcinoma that arises against the background of clonal growth of EBV-infected epithelial cells of the gastric mucosa. This subtype of tumors has unique genetic and epigenetic...

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  • publication . Article . 2020
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>Autophagy and epithelial-to-mesenchymal transition (EMT) are the main biological processes involved in tumor progression, and are closely linked. On the one hand, activation of autophagy provides energy and essential nutrients for EMT during the metastases sprea...

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  • publication . Article . 2020
    Open Access
    Authors:
    T. I. Kushnir; N. E. Arnotskaya; I. A. Kudryavtsev; V. E. Shevchenko;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly type of primary malignant brain tumor, with a patien’s median survival rate ranging from 12 to 15 months. Over the last fifteen years, the treatment for GBM has included maximal...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    V. P. Deryagina; V. P. Reutov;
    Persistent Identifiers
    Publisher: ABV-press

    The review analyzes literature data and the results of our own research on the role of reactive nitrogen species (NO, NO 2 , N 2 O 3 ) in the initiation and progression of tumors. The possibility of modulating the activity of inducible NO synthase by the biologically ac...

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  • Background. Fine-needle aspiration biopsy is recognized as the “gold standard” in the preoperative diagnosis of thyroid cancer. However, this method does not always allow reliable differentiation between benign and malignant thyroid nodules. Thus, the cytological report...

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143 research outcomes, page 4 of 15