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143 research outcomes, page 3 of 15
  • publication . Article . 2017
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    A method is proposed for the development of an erythrocyte diagnosticum based on the evidence of patent № 2452501 (10.06.2012) via development of sensitine obtained from the serum of mares in foal, the above factor being used for diagnosis of malignant neoplasms. In ord...

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  • publication . Other literature type . Article . 2019
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    The presented review is devoted to the analysis of molecular mechanisms of action for different natural DNA-tropic compounds with established tumor preventive activity. Here we present their cancer preventive effects observed in vivo, mechanisms of DNA binding, influenc...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Spirina, L. V.; Kondakova, I. V.; Tarasenko, N. V.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>Тhe protein TRIM16 is involved in key intracellular processes, such as proliferation, cell differentiation and programmed death, including intrinsic and extrinsic apoptosis, autophagy-dependent cell death and immunogenic cell death. The TRIM16 protein acts the p...

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  • publication . Article . 2017
    Open Access
    Authors:
    D. B. Kazanskiy; Yu. Yu. Silaeva; A. A. Kalinina; M. A. Zamkova; L. M. Khromykh; N. A. Persiyantseva; L. Kh. Dzholokhava;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    In wide number of approaches to treatment of cancer immunotherapy plays special role. This approach exploits capabilities of immune system to support genetic constancy of different cells and tissues of the organism. Immunotherapy is designed to induce tumor cell destruc...

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  • publication . Article . 2016
    Open Access
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Review describes the phenomenon of RNA interference – the recently discovered biological mechanism of the negative regulation of gene expression. The mechanism is based on the block of the translation and/or degradation of messenger RNA under short non-coding RNA, among...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Semyanikhina, A. V.; Rasulov, A. O.; Lyubchenko, L. N.;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    <jats:p>Lynch syndrome was synonymous with hereditary non-polyposis colorectal cancer for a long time, however, mapping of the DNA mismatch repair (MMR) genes has led to distinguish Lynch syndrome as an independent syndromic unit from a number of Lynch-like syndromes th...

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  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    S. E. Sedykh; G. A. Nevinsky;
    Persistent Identifiers
    Publisher: Publishing House ABV Press

    Bispecific antibody molecules contain two different antigen-binding centers. Particular interest in bispecific antibodies is due to their therapeutic application. Two preparations of therapeutic bispecific immunoglobulins, approved for use in the US and European countri...

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  • publication . Article . 2015
    Open Access
    Publisher: Publishing House ABV Press

    Sex hormones, regulating normal physiological processes of most tissues and organs, are considered to be one of the key factors in the development and progression of the reproductive system cancer. Recently, the importance of the system for post-transcriptional control ...

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  • publication . Article . 2015
    Open Access
    Publisher: Publishing House ABV Press

    This review deals with the analysis of up-to-date concepts of the human neuroendocrine tumors (NETs) of the digestive system, which are a heterogeneous group of epithelial neoplasms arising from the diffuse neuroendocrine system of the gastrointestinal tract and pancrea...

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  • publication . Article . Other literature type . 2018
    Open Access Russian
    Persistent Identifiers
    Publisher: ABV-press

    <jats:p>Background. It is generally accepted that crosstalk between the growth factor receptor and ER pathways implicated in tamoxifen resistance. The aim of the study was to examine the relationship between mRNA level, protein expression and gene polymorphism of the EG...

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143 research outcomes, page 3 of 15