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88 research outcomes, page 5 of 9
  • <jats:p>Preclinical safety evaluation is an important stage in the development of medicinal products. Clinical laboratory studies, including haematological, biochemical and pathomorphological studies, are an essential part of chronic toxicity studies. A careful choice o...

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  • publication . Article . 2018
    Open Access
    Persistent Identifiers
    Publisher: SCEEMP

    The article presents general data on the chemical composition and properties of snake venoms, as well as the history of their use in medical practice. It considers the differences characteristic of the venom of snakes belonging to different systematic groups. It demonst...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Sorokina, A. V.; Alekseeva, S. V.; Eremina, N. V.; Durnev, A. D.;
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    <jats:p>Chronic toxicity studies are an integral part of the overall toxicological evaluation of drug candidates. Biochemical studies of blood and urine serve to describe the general picture of the animal’s condition and to trace the dynamics of laboratory markers of or...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Engalycheva, G. N.; Subaev, R. D.; Gorachev, D. V.; Olefir, Yu. V.;
    Persistent Identifiers
    Publisher: SCEEMP

    <jats:p>The article dwells upon the results of comparative analysis of the Russian national requirements  and EAEU regulations dealing with evaluation of preclinical pharmacological studies. It highlights historical aspects of elaboration of regulatory requirements and ...

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  • publication . Article . 2018
    Open Access Russian
    Authors:
    K. А. Koshechkin;
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    This article describes the results of Laboratory Information Management System implementation in an expert institution dealing with medicines evaluation. The purpose of the study was to evaluate the feasibility of providing digital support to the laboratories of the Fed...

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  • publication . Article . Other literature type . 2018
    Open Access Russian
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    <jats:p>The article summarises the results of studies of hydrophilic  interaction  liquid chromatography performed  from 2013 until 2017. The analysis of results obtained  during separation  of a number  of model mixtures of compounds  having different nature  helped to...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    <jats:p>One of the prerequisites for successful application of nuclear medicine technologies is the production and clinical use of radiopharmaceuticals (RPs) of a reliably high quality. The aim of the review is to discuss specific properties of RPs, which stipulate spec...

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  • publication . Article . 2018
    Open Access Russian
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    At present all new medicinal products and cosmetics that absorb medium-wavelength UVB, long-wavelength UVA, or visible light in the range 290–700 nm need to be tested for potential phototoxicity. phototoxicity is evaluated by both in vitro and in vivo methods. There are...

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  • The article looks into the main problems of determination of iodine trace amounts in multivitamins by inductively coupled plasma-atomic emission spectrometry (ICP-AES), i.e. spectral overlaps attributable to macro-components, and the background effect of organic compoun...

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  • publication . Article . Other literature type . 2018
    Open Access Russian
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    Neuropsychological research methods are used to evaluate cognitive functions (CF). Tests used in clinical neuropsychology, in most cases, describe one or more aspects of cognitive domains that are theoretical «constructs» in which several cognitive processes are involve...

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88 research outcomes, page 5 of 9