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88 research outcomes, page 4 of 9
  • publication . Article . 2018
    Open Access Russian
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    The article compares test methods and levels of requirements laid out in the world’s leading pharmacopoeias and in manufacturers’ specifications with regard to the quality of levonorgestrel and ethinyl estradiol containing medicinal products used as oral contraceptives....

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  • The assessment of allergic risk at the preclinical stage of drug development has been a debatable issue due to the integration of national requirements for medicines authorisation with those of the Eurasian Economic Union (EAEU). The article summarises mechanisms and fa...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Authors:
    Batuashvili, T. A.; Simutenko, L. V.; Shadrin, P. V.; Neugodova, N. P.;
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    <jats:p>The paper considers insulin’s specific action on the patient’s body, types of insulin preparations and insulin analogues which are used for the treatment of diabetes, as well as applicable requirements for these products. It was demonstrated that determination o...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Bezyazychnaya, A. A.; Shormanov, V. K.; Siplivaya, L. E.;
    Persistent Identifiers
    Publisher: SCEEMP

    Cefepime (active substance ‒ cefepime dihydrochloride monohydrate) is a fourth-generation antibiotic with a broad spectrum of action. The study of the chemical and toxicological properties of cefepime is especially relevant because there have been some cases of poisonin...

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  • publication . Other literature type . Article . 2019
    Open Access
    Persistent Identifiers
    Publisher: SCEEMP

    <jats:p>The «cut-and-pressed granules» dosage form was developed to improve the technological properties of cut and powdered herbal substances in order to compensate for their insufficient flowability, as well as to facilitate dosing, reduce the contamination of the pro...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Sakanyan, E. I.; Tereshina, N. S.; Lyakina, M. N.;
    Persistent Identifiers
    Publisher: SCEEMP

    <jats:p>The article describes the status of homeopathic medicines standardisation in the leading world pharmacopoeias. It reviews main requirements for raw materials of plant, animal, and mineral origin, which are used in the production of homeopathic medicines. It also...

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  • publication . Article . 2018
    Open Access
    Persistent Identifiers
    Publisher: SCEEMP

    The article describes theoretical foundations and successful experimental testing of a modified method of intravitreal injection (IVI) in the rabbit eye performed in the laboratory. The method needed modification because preoperative preparation described in available g...

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  • publication . Other literature type . Article . 2019
    Open Access
    Persistent Identifiers
    Publisher: SCEEMP

    <jats:p>Spontaneous preterm birth is one of the most pressing issues in obstetrics, as it remains one of the leading causes of newborn morbidity and mortality. Pending issues of aetiology, pathogenesis, and absence of medicinal products indicated for the treatment of sp...

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  • publication . Article . Other literature type . 2019
    Open Access Russian
    Persistent Identifiers
    Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”

    <jats:p>In 2016 the WHO Assembly defined a global strategy to combat viral hepatitis viruses, which seeks to eliminate these infections by 2030. The most important goals of this programme, adopted by 194 countries, are to reduce the incidence of viral hepatitis by 90 % ...

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  • publication . Other literature type . Article . 2019
    Open Access
    Persistent Identifiers
    Publisher: SCEEMP

    The quality and effectiveness of preclinical trials of medicines depend on compliance with the Good Laboratory Practice (GLP) principles. At the same time, the data of the World Health Organisation (WHO) and the analysis of the regulatory framework suggest that the reli...

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88 research outcomes, page 4 of 9