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  • Closed Access
    Authors: 
    Yu, Yan; Yan, YiZhong; Luo, Zhen; Luo, Pan; Xiao, Na; Sun, Xuan; Cheng, LaMei;
    Publisher: Elsevier BV

    Abstract Perinatal brain injury can cause death in the neonatal period and lifelong neurodevelopmental deficits. Stem cell transplantation had been proved to be effective approach to ameliorate neurological deficits after brain damage. In this study we examine the effec...

  • Open Access
    Authors: 
    Toshihiko Iuchi; K. Hatano; Ryusuke Hara; M. Saito; D. Setoguchi; S. Ikegami; Yuzo Hasegawa;
    Publisher: Elsevier BV
  • Open Access
    Authors: 
    Gabrielle Yeaney; Daniel J. Brat;
    Publisher: Oxford University Press (OUP)

    World Health Organization (WHO) central nervous system tumor classification represents the primary source of updates on diagnostic classes, grades, and criteria. However, recent and ongoing advances in molecular pathogenesis warrant more rapid integration into clinical ...

  • Authors: 
    Masaki Shimizu; Tetsujiro Shirahashi; Mao Mizuta; Yasuhiro Ikawa; Akihiro Yachie;
    Publisher: Ovid Technologies (Wolters Kluwer Health)
  • Authors: 
    Osamu Yokota; Tomoko Miki; Seishi Terada; Norihito Yamada;
    Publisher: BMJ

    Frontotemporal lobar degeneration (FTLD) is a complex clinicopathological concept comprising several fatal neurodegenerative diseases. Clinically, behavioural change, language impairment, semantic memory deficits, motor neuron signs, parkinsonism and apraxia can develop...

  • Open Access English
    Authors: 
    Izolde Bouloukaki; Ludger Grote; Walter T. McNicholas; Jan Hedner; Johan Verbraecken; Gianfranco Parati; Carolina Lombardi; Ozen K. Basoglu; Athanasia Pataka; Oreste Marrone; +3 more
    Publisher: Amer Acad Sleep Medicine
    Countries: Belgium, Turkey

    Study Objectives: the association of mild obstructive sleep apnea (OSA) with important clinical outcomes remains unclear. We aimed to investigate the association between mild OSA and systemic arterial hypertension (SAH) in the European Sleep Apnea Database cohort. Metho...

  • Open Access English
    Authors: 
    Michael W. Williams; Chih Ying Li; Catherine Cooper Hay;

    Abstract Objective To establish reliability and validity of the abbreviated (10-item) Center for Epidemiologic Studies Depression Scale (CESD-10) among individuals post stroke. Method The psychometric properties of the CESD-10 were evaluated in 1219 adults with stroke a...

  • Open Access
    Authors: 
    Stephanie Thompson; Jeroen Douwes; Alan Barber; Dominique A Cadilhac; Harry McNaughton; John Gommans; John N. Fink; Alan T. Davis; Valery L. Feigin; Anna Ranta;
    Publisher: BMJ

    IntroductionThe REGIONS Care study assesses stroke care throughout New Zealand. It includes a national audit and here we present organisational survey results assessing current availability of interventions and management approaches in each hospital.MethodsAll 20 Distri...

  • Open Access
    Authors: 
    A. Espitia; L. Duarte;
    Publisher: Elsevier BV

    Resumen Introduccion Al realizar una evaluacion neuropsicologica, es necesario contar con datos normativos adecuados; la calidad metodologica de los estudios que los proponen garantiza que las conclusiones sean confiables y validas. Se presentan las caracteristicas meto...

  • Open Access
    Authors: 
    Oeckl, Patrick; Weydt, Patrick; Steinacker, Petra; Anderl-Straub, Sarah; Nordin, Frida; Volk, Alexander E; Diehl-Schmid, Janine; Andersen, Peter M; Kornhuber, Johannes; Danek, Adrian; +14 more
    Publisher: BMJ
    Country: Belgium
    Project: EC | FAIR-PARK-II (633190)

    ObjectiveTo investigate the role of neuroinflammation in asymptomatic and symptomatic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) mutation carriers.MethodsThe neuroinflammatory markers chitotriosidase 1 (CHIT1), YKL-40 and glial fibrillary acid...

  • Authors: 
    Ali Yilmaz; Durmus Oguz Karakoyun; Hasan Serdar Işik; Sedat Bostan;
    Publisher: Turkish Neurosurgical Society

    AIM: The aim of this study was to reveal the impacts of the novel coronavirus 2019 (COVID-19) pandemic on the functioning of neurosurgery clinics and to determine the anxiety levels and attitudes of Turkish neurosurgeons towards their profession during the pandemic. MAT...

  • Publication . Article . 2019
    Closed Access
    Authors: 
    Kengo Maeda;
    Publisher: Elsevier BV

    Akinetopsia is a quite rare symptom. Two types of akinetopsia have been reported: one is cinematographic vision, and the other is invisibility of moving objects. These symptoms are thought to occur due to dysfunction of the MT/V5 area at the occipitoparietal region. I h...

  • Open Access
    Authors: 
    Wei-Xing Pan; Arthur Yin Fan; Shaozong Chen; Sarah Faggert Alemi;
    Publisher: Elsevier BV

    Sepsis is a serious medical condition in which immune dysfunction plays a key role. Previous treatments focused on chemotherapy to control immune function; however, a recognized effective compound or treatment has yet to be developed. Recent advances indicate that a neu...

  • Closed Access
    Authors: 
    Hong Liu; Haoling Tang; Wei Wei; Gesheng Wang; Yong Du; Jianghai Ruan;
    Publisher: Elsevier BV

    Abstract Objective To investigate whether the parameters of EEG microstates changed before and after an absence seizure episode. Methods AE patients with a current high frequency of seizures were included (n=21). Each included subject underwent a two-hour and 19-channel...

  • Open Access
    Authors: 
    Vidhi Kapoor; Raffaele Ferri; Mark A. Stein; Chris Ruth; Jennifer Reed; Lourdes M. DelRosso;
    Publisher: American Academy of Sleep Medicine (AASM)

    STUDY OBJECTIVES: Restless sleep is a very common parental complaint in children with attention-deficit/hyperactivity disorder (ADHD), but restless sleep has been seen in association with other comorbidities such as restless legs syndrome and obstructive sleep apnea. Re...

  • Closed Access
    Authors: 
    Sameer A. Kunte; Drew Anderson; Kiersten Brown-Espaillat; Michael T. Froehler;
    Publisher: Elsevier BV

    Abstract Objectives Stroke patients are frequently transported to a comprehensive stroke center for treatment, either from a regional hospital via interhospital transfer or from the field via direct-from-scene transfer, by air or ground transportation. We sought to dete...

  • Open Access
    Authors: 
    Sisi Li; Jiani Chen; Xin Tong; Ammar Taha Abdullah Abdulaziz; Xu Liu; Minglian Su; Chiyi Wang; Zhengchi Li; Dong Zhou;
    Publisher: Elsevier BV

    Abstract Purpose This study was conducted to investigate the relevant demographics and clinical factors contributing to seizure-related motor vehicle accidents in west China. Methods All driving patients who visited our epilepsy clinic in the West China Hospital, betwee...

  • Open Access
    Authors: 
    Lueck, Christian J;
    Publisher: BMJ

    Vogt-Koyanagi-Harada syndrome (VKHS) is a multisystem disorder that typically presents with bilateral uveitis, often associated with neurological and/or audiological features. However, it can present with neurological features before the ocular changes become apparent. ...

  • Open Access English
    Authors: 
    Elliott, Elizabeth; Newton, Judith; Rewaj, Phillipa; Gregory, Jenna M.; Tomarelli, Lynda; Colville, Shuna; Chandran, Siddharthan; Pal, Suvankar; On behalf of the Care-Mnd Consortium;
    Country: United Kingdom

    Objectives: People with motor neurone disease (pwMND) experience communication impairments due to speech and motor dysfunction. Communication support in the form of Augmentative and Alternative Communication (AAC) in conjunction with Assistive Technology (AT) access met...

  • Closed Access
    Authors: 
    Richard Blythe; Azza Ismail; Aaizza Naqvi;
    Publisher: Elsevier BV

    Intravenous recombinant tissue-plasminogen-activator (rtPA) and mechanical-thrombectomy (MT) are currently the only approved treatments for acute ischemic stroke. Their effectiveness was demonstrated in several clinical trials, and is therefore standard of care. Pregnan...

  • Open Access
    Authors: 
    Emine Taskiran; Sema Brandmeier; Erdinc Ozek; Ramazan Sari; Fatih Han Bolukbasi; Ilhan Elmaci;
    Country: Turkey

    AIM Intraoperative neurophysiological monitoring (IONM) monitors the functional integrity of critical neural structures by electrophysiological methods during surgery. Multimodality combines different neurophysiological methods to maximize diagnostic efficacy and provid...

  • Closed Access
    Authors: 
    Howe, Matthew D.; Furr, J. Weldon; Zhu, Liang; Edwards, Nancy J.; McCullough, Louise D.; Gonzales, Nicole R.;
    Publisher: Elsevier BV

    Abstract Objective Intracerebral hemorrhage affects approximately 2 million individuals per year. While the incidence is roughly equal in men and women, few studies have examined the influence of sex on secondary injury and associated long-term functional outcomes. Matr...

  • Closed Access
    Authors: 
    Weisong Zhao; Pengju Ma; Weiming Zhao; Biao Yang; Yue Zhang; Jinggui Song; Ping Zhang; Xuejing Yue;
    Publisher: Elsevier BV

    Abstract Background and Purpose: Currently, mechanical thrombectomy (MT) for emergent large-vessel occlusion (ELVO) has been widely used in the clinic. However, the question about whether MT provides the same benefits between posterior circulation emergent large vessel ...

  • Authors: 
    James R. Barnett; Bradley M. Fleming; Kennedy R. Geenen; Jo Sourbron; Jason H. Freedman; Patricia L. Bruno; Elizabeth A. Thiele;
    Publisher: John Libbey Eurotext

    To characterize the clinical phenotype of Sunflower syndrome. Sunflower syndrome is a rare photosensitive epilepsy syndrome characterized by highly stereotyped seizures, photosensitivity, and heliotropism. We retrospectively reviewed the medical records of patients seen...

  • Open Access
    Authors: 
    Sonia Santos-Lasaosa; R. Belvís; María L. Cuadrado; S. Díaz-Insa; A.B. Gago-Veiga; Guerrero-Peral Ál; M. Huerta; Pablo Irimia; J.M. Láinez; G. Latorre; +6 more
    Publisher: Elsevier BV

    Resumen Introduccion En los ultimos anos se ha observado que moleculas como el peptido relacionado con el gen de la calcitonina (CGRP) y, en menor grado, el peptido activador de la adenilato-ciclasa pituitaria estaban elevadas durante los ataques de migrana y en la migr...

  • Open Access
    Authors: 
    Basma Tamasas; Travis Nelson; Maida Chen;
    Publisher: American Academy of Sleep Medicine (AASM)

    STUDY OBJECTIVES: This aim of this study was to evaluate oral health and oral health-related quality of life (OHRQoL) in children with obstructive sleep apnea (OSA). METHODS: This cross-sectional study involved 31 children who had baseline polysomnography studies and in...

  • Publication . Other literature type . Article . 2019
    Open Access English
    Authors: 
    McKay, Erin C; Beck, John S; Khoo, Sok Kean; Dykema, Karl J; Cottingham, Sandra L; Winn, Mary E; Paulson, Henry L; Lieberman, Andrew P; Counts, Scott E;
    Publisher: Oxford University Press

    Vascular dementia (VaD) is cognitive decline linked to reduced cerebral blood perfusion, yet there are few therapeutic options to protect cognitive function following cerebrovascular accidents. The purpose of this study was to profile gene expression changes unique to V...

  • Closed Access
    Authors: 
    Zarkali, Angeliki; Cheng, Suk Fun; Dados, Agnes; Simister, Robert; Chandratheva, Arvind;
    Publisher: Elsevier BV

    Abstract Introduction: Atrial fibrillation (AF) is a major cause of ischemic stroke and Transient Ischemic Attack (TIA) and investigation for paroxysmal AF is recommended following an embolic brain event. In contrast, retinal ischemic monocular blindness is traditionall...

  • Closed Access
    Authors: 
    Kunal Gupta; Pavlos Texakalidis; Nicholas M. Boulis;
    Publisher: Elsevier BV

    Objectives Atypical facial pain syndromes are challenging disorders to manage and often incur limited benefit with surgery for classical trigeminal neuralgia presentations, such as microvascular decompression or ablative procedures. Neurostimulation of the trigeminal ga...

  • Open Access English
    Authors: 
    Line Abdul Rahman; Tanya N. Turan; George Cotsonis; Eyad Almallouhi; Christine A Holmstedt; Marc I. Chimowitz;

    Abstract Background The safety and efficacy of dual antiplatelet use for symptomatic intracranial atherosclerosis beyond 90 days is unknown. Data from SAMMPRIS was used to determine if dual antiplatelet therapy (DAPT) beyond 90 days impacted the risk of ischemic stroke ...

  • Closed Access
    Authors: 
    José María Narro-Donate; Francisco Javier Velasco-Albendea; Fernando García-Pérez; Mario Gomar-Alba; María José Castelló-Ruiz; José Masegosa-González;
    Publisher: Elsevier BV

    The cranial radiation-induced tumors appearance in pediatric patients treated for hematological diseases such as leukemia/T-lymphoblastic lymphoma (T-ALL/LBL) is a known phenomenon that may include lesions of different malignant degrees and require neurosurgical treatme...

  • Publication . Part of book or chapter of book . 2019
    Closed Access
    Authors: 
    Stefan Glasauer;
    Publisher: Elsevier

    Sequential Bayesian updating has been proposed as model for explaining various systematic biases in human perception, such as the central tendency, range effects, and serial dependence. The present chapter introduces to the principal ideas behind Bayesian updating for t...

  • Closed Access
    Authors: 
    Sipei Pan; Xuying Li; Liping Li; Hua Lin; Dequan Wang; Xiating Zhang; Xin Zhao; Jing Ye; Zhaoyang Huang; Yicong Lin; +5 more
    Publisher: Elsevier BV

    Abstract Objectives Two configurations of TTTTA/TTTCA expansion in SAMD12 have been identified in familial cortical myoclonic tremor with epilepsy type 1 (FCMTE1). This study investigated the clinical and neurophysiological features of FCMTE1 and their association with ...

  • Closed Access
    Authors: 
    Tomoaki Suzuki; Nobuyuki Genkai; Toshiharu Nomura; Hiroshi Abe;
    Publisher: Elsevier BV

    Abstract Background and Purpose Metal artifacts limit computational fluid dynamics analysis after coil embolization. Silent magnetic resonance angiography reduces metal artifacts and improves visualization of the residual cavity of coil-embolized aneurysms. This study i...

  • Closed Access
    Authors: 
    Schinkel-Ivy, Alison; Huntley, Andrew H.; Aqui, Anthony; Mansfield, Avril;
    Publisher: Elsevier BV
    Project: CIHR

    Abstract Background: Although perturbation-based balance training (PBT) may be effective in improving reactive balance control and/or reducing fall risk in individuals with stroke, the characteristics of reactive balance responses that improve following PBT have not yet...

  • Open Access
    Authors: 
    Jun-xiang Wang; Xia Li; Cuikun Li; Jian-Feng Liu; Hui Li; Yang-Yang Tian; Bu-Lang Gao;
    Publisher: Elsevier BV

    Abstract Purpose The performance of the Low-Profile Visualized Intraluminal Support (LVIS) stent deployed following balloon angioplasty is unknown in treating intracranial atherosclerotic stenosis, and this study was to investigate the safety and efficacy of the LVIS st...

  • Closed Access
    Authors: 
    Stephanie A. Parker; Tessa Kus; Ritvij Bowry; Nicole Gutierrez; Chunyan Cai; Jose-Miguel Yamal; Suja S. Rajan; Mengxi Wang; Asha P Jacob; Christopher Souders; +2 more
    Publisher: Elsevier BV

    Abstract Introduction Mobile Stroke Units (MSUs) deliver acute stroke treatment on-scene in coordination with Emergency Medical Services (EMS). One criticism of the MSU approach is the limited range of a single MSU. The Houston MSU is evaluating MSU implementation, and ...

  • Authors: 
    Alejandro Ballvé-Martín; Sandra Boned; Marta Rubiera;
    Publisher: Viguera Editores SLU

    Introduccion. La infeccion grave por el SARS-CoV-2 ha demostrado un incremento del riesgo de fenomenos tromboticos, especialmente venosos. Los cateteres venosos centrales tambien se han asociado a un mayor riesgo de complicaciones tromboticas. El embolismo paradojico co...

  • Publication . Other literature type . Article . 2020
    Open Access English
    Authors: 
    Sunil Sharma; Olaf Oldenburg; Henrik Fox;
    Publisher: American Academy of Sleep Medicine

    Citation:Sharma S, Oldenburg O, Fox H. Sleep apnea and pulmonary hypertension: connecting the dots. J Clin Sleep Med. 2021;17(2):347–348.

  • Open Access English
    Authors: 
    Masashi Kameyama; Koji Murakami; Masahiro Jinzaki;
    Publisher: Springer Nature

    Objective [99mTc] d,l-hexamethyl-propyeneamine oxime (99mTc-HMPAO), a brain perfusion tracer, suffers significant underestimation of regional cerebral blood flow (rCBF). Lassen et al. developed their linearization algorithm to correct the influence of back-diffusion of ...

  • Closed Access
    Authors: 
    Sarah Duval-Dachary; Jean-Philippe Chevalier-Lancioni; Mauro Rossini; Paolo Perego; Mario Covarrubias;
    Publisher: Springer International Publishing

    This document summarizes a master thesis project trying to bring a new solution to hemiplegia rehabilitation, one of the numerous consequences of strokes. A hemiplegic patients observe paralysis on one side of their body, and as so, loses autonomy and their quality of l...

  • Closed Access
    Authors: 
    Zeynep Selen Karalok; Hülya Maraş Genç; Birce Dilge Taskin; Nesrin Ceylan; Alev Güven; Nese Yarali;
    Publisher: Elsevier BV

    Abstract Background Childhood stroke causes significant morbidity and mortality. In this study, we aimed to define the presenting findings, causes, risk factors and motor outcomes of our patients. Methods We retrospectively analysed patients aged from 1 month to 18 year...

  • Open Access
    Authors: 
    Michal Tzadok; Amit Harush; Andrea Nissenkorn; Yaacov Zauberman; Zeev Feldman; Bruria Ben-Zeev;
    Publisher: Elsevier BV

    Abstract Purpose The AspireSR® is a vagal nerve stimulation (VNS) device that operates as a closed-loop system, delivering an automatic stimulation in response to an ictal heart rate increase that serves as a predictor for an imminent seizure. Our purpose is to assess t...

  • Open Access
    Authors: 
    Barbosa, Pedro Melo; Djamshidian, Atbin; O'Sullivan, Sean S; de Pablo-Fernandez, Eduardo; Korlipara, Prasad; Morris, Huw R; Bhatia, Kailash P; Limousin, Patricia; Foltynie, Thomas; Lees, Andrew J; +1 more
    Publisher: BMJ

    Impulsive compulsive behaviours (ICBs) such as dopamine dysregulation syndrome (DDS), pathological gambling, compulsive sexual behaviour, punding, compulsive shopping and binge eating are recognised complications of dopaminergic treatment that affect at least one in sev...

  • Open Access
    Authors: 
    Mangala Bhongade; Amit. A. Navare;
    Publisher: Medip Academy

    Background: Hypertension is one of major causes responsible for cardiovascular disease. Prehypertension, as defined by joint national commission-2003 as condition with SBP 120-139 or DBP as 80-89mmH, was identified as a precursor for hypertension and also associated wit...

  • Closed Access
    Authors: 
    Patricia Braga;
    Publisher: Elsevier BV

    Abstract Objective Epilepsy is a condition associated with high levels of stigma. Quality of life (QoL) is reportedly diminished in people with epilepsy worldwide. The purpose of our study was to describe and compare the self-reported QoL of people with epilepsy and peo...

  • Closed Access
    Authors: 
    Anita Ann Sunny; Rajesh Shankar Iyer; Soumya Gopalan Kumaran; Nadiya Grace Bunshaw; Karthikeyan Shanmugham; Uma Govindaraj;
    Publisher: Elsevier BV

    Abstract Objectives Anti-seizure medication (ASM) non-adherence contributes to treatment gap and increases mortality and morbidity associated with epilepsy. Beliefs about medications are considered better predictors of ASM non-adherence than clinico-demographic factors....

  • Open Access
    Authors: 
    I. Pagola; L. Torné; I Jericó; Berta Ibáñez;
    Publisher: Elsevier BV

    Introduction: ACTIVLIM is an instrument for the measurement of activity limitations in patients with neuromuscular disorders. The aim of this study is to establish a transcultural adaptation and psychometric validation of the Spanish-language version of ACTIVLIM in a sa...

  • Open Access
    Authors: 
    Beard, Richard S; Hoettels, Brian A; Meegan, Jamie E; Wertz, Travis S; Cha, Byeong J; Yang, Xiaoyuan; Oxford, Julia T; Wu, Mack H; Yuan, Sarah Y;
    Publisher: SAGE Publications

    Inflammation-induced blood–brain barrier (BBB) dysfunction and microvascular leakage are associated with a host of neurological disorders. The tight junction protein claudin-5 (CLDN5) is a crucial protein necessary for BBB integrity and maintenance. CLDN5 is negatively...

  • Closed Access
    Authors: 
    Xiaoyun Liu; Yuxiang Han; Liling Yang; Bao Wang; Sai Shao; Yabo Feng; Zaiying Pang; Yifeng Du; Youting Lin;
    Publisher: Elsevier BV

    Abstract Purpose The purpose of this study was to characterize the spectrum of motor events in patients with acute anti-leucine-rich glioma-inactivated protein 1 (anti-LGI1) encephalitis through video-electroencephalogram (VEEG) recordings. Method We collected data retr...