Abstract Perinatal brain injury can cause death in the neonatal period and lifelong neurodevelopmental deficits. Stem cell transplantation had been proved to be effective approach to ameliorate neurological deficits after brain damage. In this study we examine the effec...

World Health Organization (WHO) central nervous system tumor classification represents the primary source of updates on diagnostic classes, grades, and criteria. However, recent and ongoing advances in molecular pathogenesis warrant more rapid integration into clinical ...

Frontotemporal lobar degeneration (FTLD) is a complex clinicopathological concept comprising several fatal neurodegenerative diseases. Clinically, behavioural change, language impairment, semantic memory deficits, motor neuron signs, parkinsonism and apraxia can develop...

Study Objectives: the association of mild obstructive sleep apnea (OSA) with important clinical outcomes remains unclear. We aimed to investigate the association between mild OSA and systemic arterial hypertension (SAH) in the European Sleep Apnea Database cohort. Metho...

Abstract Objective To establish reliability and validity of the abbreviated (10-item) Center for Epidemiologic Studies Depression Scale (CESD-10) among individuals post stroke. Method The psychometric properties of the CESD-10 were evaluated in 1219 adults with stroke a...

IntroductionThe REGIONS Care study assesses stroke care throughout New Zealand. It includes a national audit and here we present organisational survey results assessing current availability of interventions and management approaches in each hospital.MethodsAll 20 Distri...

Resumen Introduccion Al realizar una evaluacion neuropsicologica, es necesario contar con datos normativos adecuados; la calidad metodologica de los estudios que los proponen garantiza que las conclusiones sean confiables y validas. Se presentan las caracteristicas meto...

ObjectiveTo investigate the role of neuroinflammation in asymptomatic and symptomatic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) mutation carriers.MethodsThe neuroinflammatory markers chitotriosidase 1 (CHIT1), YKL-40 and glial fibrillary acid...

AIM: The aim of this study was to reveal the impacts of the novel coronavirus 2019 (COVID-19) pandemic on the functioning of neurosurgery clinics and to determine the anxiety levels and attitudes of Turkish neurosurgeons towards their profession during the pandemic. MAT...

Akinetopsia is a quite rare symptom. Two types of akinetopsia have been reported: one is cinematographic vision, and the other is invisibility of moving objects. These symptoms are thought to occur due to dysfunction of the MT/V5 area at the occipitoparietal region. I h...

Sepsis is a serious medical condition in which immune dysfunction plays a key role. Previous treatments focused on chemotherapy to control immune function; however, a recognized effective compound or treatment has yet to be developed. Recent advances indicate that a neu...

Abstract Objective To investigate whether the parameters of EEG microstates changed before and after an absence seizure episode. Methods AE patients with a current high frequency of seizures were included (n=21). Each included subject underwent a two-hour and 19-channel...

STUDY OBJECTIVES: Restless sleep is a very common parental complaint in children with attention-deficit/hyperactivity disorder (ADHD), but restless sleep has been seen in association with other comorbidities such as restless legs syndrome and obstructive sleep apnea. Re...

Abstract Objectives Stroke patients are frequently transported to a comprehensive stroke center for treatment, either from a regional hospital via interhospital transfer or from the field via direct-from-scene transfer, by air or ground transportation. We sought to dete...

Abstract Purpose This study was conducted to investigate the relevant demographics and clinical factors contributing to seizure-related motor vehicle accidents in west China. Methods All driving patients who visited our epilepsy clinic in the West China Hospital, betwee...

Vogt-Koyanagi-Harada syndrome (VKHS) is a multisystem disorder that typically presents with bilateral uveitis, often associated with neurological and/or audiological features. However, it can present with neurological features before the ocular changes become apparent. ...

Objectives: People with motor neurone disease (pwMND) experience communication impairments due to speech and motor dysfunction. Communication support in the form of Augmentative and Alternative Communication (AAC) in conjunction with Assistive Technology (AT) access met...

Intravenous recombinant tissue-plasminogen-activator (rtPA) and mechanical-thrombectomy (MT) are currently the only approved treatments for acute ischemic stroke. Their effectiveness was demonstrated in several clinical trials, and is therefore standard of care. Pregnan...

AIM Intraoperative neurophysiological monitoring (IONM) monitors the functional integrity of critical neural structures by electrophysiological methods during surgery. Multimodality combines different neurophysiological methods to maximize diagnostic efficacy and provid...

Abstract Objective Intracerebral hemorrhage affects approximately 2 million individuals per year. While the incidence is roughly equal in men and women, few studies have examined the influence of sex on secondary injury and associated long-term functional outcomes. Matr...

Abstract Background and Purpose: Currently, mechanical thrombectomy (MT) for emergent large-vessel occlusion (ELVO) has been widely used in the clinic. However, the question about whether MT provides the same benefits between posterior circulation emergent large vessel ...

To characterize the clinical phenotype of Sunflower syndrome. Sunflower syndrome is a rare photosensitive epilepsy syndrome characterized by highly stereotyped seizures, photosensitivity, and heliotropism. We retrospectively reviewed the medical records of patients seen...

Resumen Introduccion En los ultimos anos se ha observado que moleculas como el peptido relacionado con el gen de la calcitonina (CGRP) y, en menor grado, el peptido activador de la adenilato-ciclasa pituitaria estaban elevadas durante los ataques de migrana y en la migr...

STUDY OBJECTIVES: This aim of this study was to evaluate oral health and oral health-related quality of life (OHRQoL) in children with obstructive sleep apnea (OSA). METHODS: This cross-sectional study involved 31 children who had baseline polysomnography studies and in...

Vascular dementia (VaD) is cognitive decline linked to reduced cerebral blood perfusion, yet there are few therapeutic options to protect cognitive function following cerebrovascular accidents. The purpose of this study was to profile gene expression changes unique to V...

Abstract Introduction: Atrial fibrillation (AF) is a major cause of ischemic stroke and Transient Ischemic Attack (TIA) and investigation for paroxysmal AF is recommended following an embolic brain event. In contrast, retinal ischemic monocular blindness is traditionall...

Objectives Atypical facial pain syndromes are challenging disorders to manage and often incur limited benefit with surgery for classical trigeminal neuralgia presentations, such as microvascular decompression or ablative procedures. Neurostimulation of the trigeminal ga...

Abstract Background The safety and efficacy of dual antiplatelet use for symptomatic intracranial atherosclerosis beyond 90 days is unknown. Data from SAMMPRIS was used to determine if dual antiplatelet therapy (DAPT) beyond 90 days impacted the risk of ischemic stroke ...

The cranial radiation-induced tumors appearance in pediatric patients treated for hematological diseases such as leukemia/T-lymphoblastic lymphoma (T-ALL/LBL) is a known phenomenon that may include lesions of different malignant degrees and require neurosurgical treatme...

Sequential Bayesian updating has been proposed as model for explaining various systematic biases in human perception, such as the central tendency, range effects, and serial dependence. The present chapter introduces to the principal ideas behind Bayesian updating for t...

Abstract Objectives Two configurations of TTTTA/TTTCA expansion in SAMD12 have been identified in familial cortical myoclonic tremor with epilepsy type 1 (FCMTE1). This study investigated the clinical and neurophysiological features of FCMTE1 and their association with ...

Abstract Background and Purpose Metal artifacts limit computational fluid dynamics analysis after coil embolization. Silent magnetic resonance angiography reduces metal artifacts and improves visualization of the residual cavity of coil-embolized aneurysms. This study i...

Abstract Background: Although perturbation-based balance training (PBT) may be effective in improving reactive balance control and/or reducing fall risk in individuals with stroke, the characteristics of reactive balance responses that improve following PBT have not yet...

Abstract Purpose The performance of the Low-Profile Visualized Intraluminal Support (LVIS) stent deployed following balloon angioplasty is unknown in treating intracranial atherosclerotic stenosis, and this study was to investigate the safety and efficacy of the LVIS st...

Abstract Introduction Mobile Stroke Units (MSUs) deliver acute stroke treatment on-scene in coordination with Emergency Medical Services (EMS). One criticism of the MSU approach is the limited range of a single MSU. The Houston MSU is evaluating MSU implementation, and ...

Introduccion. La infeccion grave por el SARS-CoV-2 ha demostrado un incremento del riesgo de fenomenos tromboticos, especialmente venosos. Los cateteres venosos centrales tambien se han asociado a un mayor riesgo de complicaciones tromboticas. El embolismo paradojico co...

Citation:Sharma S, Oldenburg O, Fox H. Sleep apnea and pulmonary hypertension: connecting the dots. J Clin Sleep Med. 2021;17(2):347–348.