Advanced search in
Research products
arrow_drop_down
Searching FieldsTerms
Any field
arrow_drop_down
includes
arrow_drop_down
Include:
142,959 Research products, page 1 of 14,296

  • Publications
  • Research data
  • Other research products
  • 2018-2022
  • Open Access
  • Report

10
arrow_drop_down
Relevance
arrow_drop_down
  • Open Access Spanish
    Authors: 
    Tumi Quispe, Jesús E; Escobar Mamani, Fortunato;
    Publisher: Universidad Nacional del Altiplano

    RESUMEN El estudio analizó los factores sociales y políticos que inciden en la priorización de la inversión ambiental en la gestión del gobierno regional de Puno. El diseño de investigación fue no experimental, transversal, documental y cuantitativo de carácter descriptivo; la unidad de análisis estuvo conformado por los directivos de las organizaciones de la sociedad civil y las autoridades y funcionarios del gobierno regional. La población operacional, determinada al azar, considerando el 95% grado de confianza y margen de error de 0.05, fue de 160 directivos de la sociedad civil. La recolección de la data, en lo medular, se realizó a través de una encuesta aplicada en el año 2017, cuyo procesamiento y sistematización fue en el software estadístico SPSS. Los resultados inducen que la inversión en la agenda ambiental en la gestión pública regional de Puno está condicionado por la articulación de las orientaciones estratégicas y programáticas que establece el plan de desarrollo regional concertado (PDRC) y la institucionalidad ambiental que le asignan una prioridad sustancial en la inversión ambiental; con las iniciativas y demandas de las autoridades locales y organizaciones de la sociedad civil y la voluntad política de las autoridades regionales, dado su óptica pragmática y visión cortoplacista, la inversión en proyectos estratégicos ambientales son mínimos y poco significativos, el cual se evidencia en el proceso de formulación e implementación del presupuesto participativo ABSTRACT The study analyzed the social and political factors that affect the prioritization of environmental investment in the management of the regional government of Puno. The research design was non-experimental, transversal, documentary and quantitative of a descriptive nature; the unit of analysis was made up of the leaders of civil society organizations and the authorities and officials of the regional government. The operational population, determined at random, considering the 95% degree of confidence and margin of error of 0.05, was 160 executives from civil society. The data collection, in the core, was carried out through a survey applied in the year 2017, whose processing and systematization was in the statistical software SPSS. The results induce that the investment in the environmental agenda in the regional public management of Puno is conditioned by the articulation of the strategic and programmatic orientations established by the concerted regional development plan (PDRC) and the environmental institutionality that assign it a substantial priority in environmental investment; With the initiatives and demands of local authorities and civil society organizations and the political will of regional authorities, given its pragmatic perspective and short-term vision, investment in strategic environmental projects is minimal and not significant, which is evident in the process of formulation and implementation of the participatory budget

  • Publication . Report . 2018
    Open Access
    Authors: 
    K. J. Palladino;
    Publisher: Office of Scientific and Technical Information (OSTI)
  • Open Access
    Authors: 
    Barnett Berry; P. Ann Byrd;
    Publisher: Digital Promise

    This paper points to teaching policy issues that need to be addressed if micro-credentials are going to spur the transformation of professional learning that researchers call for and teachers seek. The paper also documents what a growing number of states and districts, as well as the nation's largest teachers' union, are doing with micro-credentials.

  • Open Access English

    The occurrence of microplastics in the environment has attracted attention in recent years. This is particularly evident in the huge volumes of initiatives, research, projects and actions that are taking place both internationally and in Sweden. The Swedish Environmental Protection Agency (Swedish EPA) sees the occurrence of microplastics in the environment as an important ongoing issue. While we are dependent on synchronisation of results within the EU and other countries, and sometimes have to wait for others’ results, our own work in Sweden needs to continue. The Swedish EPA considers that the conditions for reducing the dispersal of microplastics in the environment has been improved by the measures it proposes here. To continue making progress, we need to increase our knowledge of sources, dispersal and effects. Proposals for action The Swedish EPA proposes that the Government: Introduces a notification requirement for facilities using artificial grass and moulded granulate surfaces and for equestrian arenas containing rubber or plastics. The Swedish EPA undertakes to be a national knowledge node for microplastics in the environment. We consider that in the immediate future, the greatest need will lie in the collection and dissemination of knowledge. The measures below could be included as part of this node work and be, to a large extent, financed by the increase requested in the Swedish EPA’s budget. Measures for supervisory guidance for artificial grass pitches and other outdoor facilities for sports and play. Continued financing of pre-procurement purchasing group for artificial grass. Work towards a change in criteria in the Ecodesign Directive for washing machines. Promote the use of domestic filter solutions for households. Measures for laundries. The Swedish EPA also undertakes to support other authorities as a knowledge node by taking in, collecting and disseminating new knowledge. The agency considers it appropriate for this responsibility be evaluated and reviewed after five years. Commission The Swedish EPA has focused on quantified land-based sources. We are reducing the gaps in knowledge and providing the action proposals above. An important starting point for the current commission is the list of the largest emission sources and important dispersion routes presented by the Swedish EPA in its first commission in May 2017. The largest quantified source, road traffic, is handled by VTI, the Swedish National Road and Transport Research Institute, in a separate commission. The second and fourth largest sources, artificial grass pitches and washing of textiles, are handled in this commission. The work on the third largest source, boat hulls, is coordinated by the Swedish Transport Agency. Litter is probably a major source of microplastics – perhaps the largest – but very difficult to quantify. In view of the EU’s extensive work, for example on its plastic strategy, the recently adopted single-use plastics directive, and ongoing national efforts, such as information dissemination, beach cleaning and the recent concluded inquiry on sustainable plastic use, the Swedish EPA has chosen not to investigate this source in more detail in this commission. The Swedish EPA reports new sources, such as construction and demolition waste, and other uses of artificial grass. In its proposed measures, the Swedish EPA has not intended to anticipate the results from the inquiry Giftfri och cirkulär återföring av fosfor från avloppsslam [Non-toxic and circular return of phosphorus from sewage sludge], and the commissions of the Swedish National Road and Transport Research Institute (VTI) and the Swedish Food Agency (Livsmedelsverket), respectively. New knowledge of occurrence and effects Knowledge of the presence and effects of microplastics in surface waters in lakes and oceans has increased in recent years. However, the presence and effects in soil and air and the health risks to humans are less well-known. There is a consensus among researchers that the negative effects increase the smaller the particles are. On 30 April 2019, the EU Commission’s scientific advisory function, SAM, published a scientific opinion. This outlines increasing concern about the presence of microplastics in air, soil and sediment. It also noted that, although ecological risks are rare at present, there are at least a few local areas, in coastal waters and sediments, in which effects could occur. If future emissions remain at the same level as today or increase, the risks may be extensive within a century. The report has also listed possible measures, such as incorporating microplastics into relevant directives or reducing emissions at source. New knowledge of artificial grass pitches, outdoor facilities and textiles Knowledge of emissions from artificial grass pitches, textile production and laundry facilities has increased. We can, with greater certainty, quantify emissions from artificial grass pitches that result in lower, but still large, total emissions than previously estimated. However, knowledge of emissions from other outdoor sports and play facilities is comparatively low. The size of the area involved, the size of the total emissions, life expectancy, etc. are areas where more knowledge is needed. The emissions from textile production are estimated to be significantly lower than those from laundry facilities, partly because the number of production plants is low in Sweden, compared to the number of laundry facilities. The largest amounts of microplastics from textile washing are still assumed to come from domestic washing. There are already examples of filter solutions that can be installed on washing machines meant to reduce emission of microplastics into the output water, but their efficacy needs to be verified. There is also a need to ensure that the use of filter solutions does not contribute to a conflict of objectives between different environmental impact categories, such as increased energy consumption and climate impact. The Swedish EPA sees a need for further analyses. No new findings have been made which would reverse or drastically alter either the previous understanding of the major sources or the order of size of emissions. We have, however, expanded our knowledge base in certain areas. New knowledge of dispersal pathways Knowledge of what happens to microplastics in wastewater treatment plants has increased. A new study shows that microplastics are present in more purification stages than previously noted and that there are still significant uncertainties in the measurement results. Previous analyses showing a 95–99 % purification rate in outgoing water have been verified. For storm water, a study of storm water wells in Gothenburg shows the presence of microplastics, which are largely assumed to come from tyre wear and road surfacing.

  • Open Access English
    Authors: 
    Pezzutto,Alessandro; Sirolli,Vittorio; Di Liberato,Lorenzo; Morroni,Manrico; Bonomini,Mario;
    Publisher: Dove Press

    Alessandro Pezzutto,1 Vittorio Sirolli,1 Lorenzo Di Liberato,1 Manrico Morroni,2 Mario Bonomini1 1Department of Medicine, Nephrology and Dialysis Unit, SS Annunziata Hospital, “G. d’Annunzio” University, Chieti, Italy; 2Department of Experimental and Clinical Medicine-Neuroscience and Cell Biology, School of Medicine, Università Politecnica delle Marche, Ancona, ItalyCorrespondence: Vittorio Sirolli Email vsirolli@unich.itBackground: Immunoglobulin A deficiency (IgAD) is the most common form of primary immunodeficiency in western countries. It can be associated with the development of autoimmune diseases both in adults and in children even though the exact pathophysiology is not fully defined.Case Presentation: We report here a case of a young patient who developed nephrotic syndrome secondary to membranoproliferative glomerulonephritis associated with the incidental finding of IgAD. We began corticosteroid therapy and angiotensin-converting enzyme inhibitor, and we observed partial remission of the nephrotic syndrome after about nine months; nonetheless, in the following follow-up visits, a progressive decline of renal function was found.Conclusion: Our case extends the spectrum of hitherto described glomerulonephritides associated with IgAD which were described until now.Keywords: membranoproliferative glomerulonephritis, IgA deficiency, nephrotic syndrome

  • Open Access English
    Authors: 
    Ellis, John; Lew, Jeffrey; Brahmbhatt, Sumir; Gordon, Sarah; Denunzio, Troy;
    Publisher: Hindawi

    Background. Erythrodermic psoriasis is a rare and severe variant of psoriasis. It is characterized by widespread skin erythema, scaling, pustules, or exfoliation of more than 75% of the body’s surface area. This condition has life-threatening complications to include hemodynamic, metabolic, immunologic, and thermoregulatory disturbances. One metabolic complication, hyperuricemia, occurs from rapid keratinocyte differentiation and infiltration of inflammatory cells into psoriatic lesions. Although renal injury caused by shunting of blood to the skin has been reported, there are no reports of erythrodermic psoriasis causing crystal-induced nephropathy. We present a case of erythrodermic psoriasis and hyperuricemia complicated by uric acid crystal nephropathy. Case Presentation. A 57-year-old male with long-standing psoriatic arthritis presented with diffuse scaling of his skin. He was being treated with adalimumab, leflunomide, and topical clobetasol, but had recently stopped taking his medications. Physical exam revealed yellow scaling covering his entire body with underlying erythema and tenderness without mucosal involvement. Labs were notable for a creatinine of 3.3 mg/dL, with no prior history of renal disease, and uric acid of 12.7 mg/dL. He was admitted to the intensive care unit given >80% of body surface area involvement and acute renal failure. Despite aggressive fluid resuscitation, renal function did not improve, and creatinine peaked at 4.61 mg/dL. Urine microscopy showed diffuse polymorphic uric acid crystals, consistent with uric acid crystal-induced nephropathy. He was started on rasburicase, urinary alkalinization, and fluids. His renal function improved dramatically; urine output, uric acid, and electrolytes normalized. He was discharged on topical clobetasol and leflunomide and started on secukinumab with little to no skin involvement. Conclusion. This case presents the rare complication of crystal-induced nephropathy in a patient with erythrodermic psoriasis. Uric acid crystal nephropathy is well described in diseases with rapid cell turnover such as tumor lysis syndrome. It is thought that rapid keratinocyte differentiation and inflammatory infiltration of psoriatic lesions produced life-threatening electrolyte abnormalities similar to tumor lysis syndrome. Early recognition of this rare complication is critical, and aggressive fluid resuscitation, urine alkalinization, and uric acid lowering agents should be administered immediately.

  • Open Access
    Authors: 
    David Rosner;
    Publisher: Milbank Memorial Fund
  • Open Access
    Authors: 
    Álvaro Hidalgo;
    Publisher: Fundación Weber
  • Publication . Report . 2019
    Open Access
    Authors: 
    CICERO Shades of Green AS;
    Publisher: CICERO Shades of Green AS

    Category: Second Opinion, Sector: Real Estate, Issuer type: Corporate, Shading: Medium Green

  • Open Access
    Authors: 
    Bruce Appleyard; Chris Allen; Jonathan Stanton;
    Publisher: Mineta Transportation Institute
Send a message
How can we help?
We usually respond in a few hours.