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103 research outcomes, page 1 of 11
  • publication . Article . 2018
    Open Access
    Authors:
    Editorial article;
    Persistent Identifiers
    Publisher: SCEEMP

    .

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  • publication . Article . 2018
    Open Access
    Authors:
    T. Yu. Kozlova; L. M. Khantimirova; A. V. Rukavishnikov; V. A. Shevtsov;
    Persistent Identifiers
    Publisher: SCEEMP

    This article provides a review on efficacy and safety of tick-borne encephalitis vaccines licensed in the Russian Federation. It highlights that both Russian and imported tick-borne encephalitis vaccines demonstrate high immunogenicity, safety and epidemiological effect...

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  • publication . Article . 2018
    Open Access Russian
    Authors:
    S. S. Kurashova; T. K. Dzagurova; A. A. Ishmukhametov; M. S. Egorova; M. V. Balovneva; S. E. Sotskova; E. A. Tkachenko;
    Persistent Identifiers
    Publisher: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»

    Addition of adjuvants is a generally recognized method of enhancing the immunogenicity of vaccines. There is a large variety of adjuvants, therefore the choice of an adjuvant is based on the comparison of adjuvants efficacy in animal models, as well as assessment of the...

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  • publication . Article . 2018
    Open Access
    Authors:
    I. A. Alekseeva; O. V. Perelygina;
    Persistent Identifiers
    Publisher: SCEEMP

    The study performed as part of evaluation of immunobiological properties of Bordetella pertussis vaccine strains offered an opportunity to standardize pertussis bacterial mass based on the content of surface antigens — agglutinogens 1, 2 and 3. Certain levels of aggluti...

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  • publication . Article . 2021
    Open Access
    Authors:
    E. G. Abramova; A. V. Komissarov; N. V. Sinitsyna; I. M. Zhulidov; A. K. Nikiforov;
    Persistent Identifiers
    Publisher: SCEEMP

    At the moment, there are no scientific publications devoted to the technological aspects of production of immunoglobulin solid dosage forms. The aim of the study was to review Russian and foreign literature on production of immunoglobulin solid dosage forms, and present...

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  • publication . Article . 2018
    Open Access
    Authors:
    G. A. Trusov; A. A. Chaplenko; I. S. Semenova; E. V. Melnikova; Yu. V. Olefir;
    Persistent Identifiers
    Publisher: SCEEMP

    Flow cytometry is the most common method of identification and quantitation of cell surface markers. Flow cytometry can be used for cell counting and characterization of cell types and subtypes by labeling cells with fluorochrome-conjugated monoclonal antibodies. Manufa...

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  • publication . Article . 2019
    Open Access
    Authors:
    Kapitanova, V. K.; Petrova, N. E.; Zhdanova, M. Yu.; Nevskaya, L. V.;
    Persistent Identifiers
    Publisher: SCEEMP

    Allergic reactions associated with sensitisation to metals are a common but underexplored problem. Due to the frequent use of metals and their alloys there has been an increase in the number of registered cases of allergic reactions. Recently there have been cases when ...

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  • publication . Article . 2018
    Open Access Russian
    Authors:
    A. A. Goryaev; L. V. Sayapina; Yu. I. Obukhov; V. P. Bondarev;
    Persistent Identifiers
    Publisher: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»

    Cholera is an acute diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and O139 serogroups. It still remains a major global healthcare problem. According to WHO, about 100,000 people die from cholera every year, despite the modern methods of treatment, ...

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  • publication . Article . 2019
    Open Access
    Authors:
    Merkulov, V. A.; Melnikova, E. V.;
    Persistent Identifiers
    Publisher: SCEEMP

    Marketing authorisation is a prerequisite for the use of drugs in medical practice in the Russian Federation. The marketing authorisation procedure is applicable to ordinary medicinal products. As for advanced therapy medicinal products containing viable human cells — t...

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  • publication . Article . 2019
    Open Access
    Authors:
    Petraneva, E. V.; Proskurina, I. A.; Goryachev, D. V.; Kovaleva, E. L.;
    Persistent Identifiers
    Publisher: SCEEMP

    The need to strengthen the post-approval regulation of biological products stems from their increasing role in the treatment of serious human diseases. Until recently, there were open questions on the classification of changes and supporting data necessary to confirm th...

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103 research outcomes, page 1 of 11