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This article describes a clinical case demonstrating the difficulties of lifetime and post-mortem diagnosis in a patient with primary myelofibrosis complicated by a generalized fungal infection caused by a rare pathogen such as Candida lusitaniae. Management of such pat...

<p>We describe an application of a cell-binding microarray – to parallel study of morphology, tartrate-resistant acid phosphatase activity and detection of surface markers on peripheral blood lymphocytes of 90  atients with suspected hairy cell leukemia (HCL). We have f...

<jats:p>The article provides a literature review about RHD and RHCE polymorphisms which encode different RhD and RhC antigen variants. The data about genes RHD and RHCE polymorphisms, RhD weak types, RhD partial types and RhC variants in Russians is presented for the fi...

Introduction. Surface immunoglobulin expression is a main immunophenotypic criteria of mature subtype of B-lineage acute lymphoblastic leukemia. Although the majority of such cases represents Burkitt leukemia/lymphoma, it was shown for several times that membrane IgM co...

Hereby we present methodological aspects and prognostic significance of minimal residual disease (MRD) monitoring in infant acute leukemias. Based on our own experience we made algorithm for detection of MRD in this group of patients. We conclude that general concordanc...

<p>Neutropenia and associated infection, resulting in hospitalization and use of antibiotics, has a negative effect on chemotherapy. The need to reduce the dose of cytotoxic drugs during neutropenia leads to lower survival rates in patients with hematological malignanci...

<jats:p><jats:bold>Objective: </jats:bold>to assess the economic outcomes of using anidulafungin (Eraxis®) in comparison with the recommended treatment regimens in adult patients with invasive candidiasis.</jats:p><jats:p><jats:bold>Materials and methods. </jats:bold>Th...

The review contains data about new important aspects of pathogenesis, and treatment of anemia of chronic diseases. The treatment of patients with anemia of chronic diseases by erythropoiesis-stimulating agents and iron is analyzed.

The article reviewed literature data relating to the methods used for detection of single tumor cells in bone marrow, lymph nodes, and peripheral blood. Sensitivity of modern detection methods is analyzed. Despite advances in the development of molecular biology and cyt...